Computational modeling and in silico analysis of differential regulation of myo-inositol catabolic enzymes in Cryptococcus neoformans

Inositol is a key cellular metabolite for many organisms. Cryptococcus neoformans is an opportunistic pathogen which primarily infects the central nervous system, a region of high inositol concentration, of immunocompromised individuals. Through the use of myo-inositol oxygenase C. neoformans can ca...

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Veröffentlicht in:	BMC molecular biology 2008-10, Vol.9 (1), p.88-88
Hauptverfasser:	Mackenzie, Emalee A, Klig, Lisa S
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Computational Biology Cryptococcal infections Cryptococcus Cryptococcus neoformans Cryptococcus neoformans - enzymology Expressed Sequence Tags Gene Expression Regulation, Enzymologic Gene Expression Regulation, Fungal Genetic aspects Hydrogen Bonding Inositol - metabolism Inositol Oxygenase - chemistry Inositol Oxygenase - genetics Inverted Repeat Sequences Mice Models, Molecular Protein Binding Protein Structure, Tertiary Sequence Alignment
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