High-Resolution Crystal Structure of an Engineered Human β₂-Adrenergic G Protein-Coupled Receptor

Heterotrimeric guanine nucleotide-binding protein (G protein)-coupled receptors constitute the largest family of eukaryotic signal transduction proteins that communicate across the membrane. We report the crystal structure of a human β₂-adrenergic receptor-T4 lysozyme fusion protein bound to the par...

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