Direct Binding of GTP Cyclohydrolase and Tyrosine Hydroxylase

The signaling functions of dopamine require a finely tuned regulatory network for rapid induction and suppression of output. A key target of regulation is the enzyme tyrosine hydroxylase, the rate-limiting enzyme in dopamine synthesis, which is activated by phosphorylation and modulated by the avail...

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Veröffentlicht in:	The Journal of biological chemistry 2008-11, Vol.283 (46), p.31449-31459
Hauptverfasser:	Bowling, Kevin M., Huang, Zhinong, Xu, Dong, Ferdousy, Faiza, Funderburk, Christopher D., Karnik, Nirmala, Neckameyer, Wendi, O'Donnell, Janis M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Enzyme Catalysis and Regulation
Online-Zugang:	Volltext
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