A Trypanosoma cruzi Phosphatidylinositol 3-Kinase (TcVps34) Is Involved in Osmoregulation and Receptor-mediated Endocytosis

Trypanosoma cruzi, the etiological agent of Chagas disease, has the ability to respond to a variety of environmental changes during its life cycle both in the insect vector and in the vertebrate host. Because regulation of transcription initiation seems to be nonfunctional in this parasite, it is im...

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Veröffentlicht in:	The Journal of biological chemistry 2008-11, Vol.283 (46), p.31541-31550
Hauptverfasser:	Schoijet, Alejandra C., Miranda, Kildare, Girard-Dias, Wendell, de Souza, Wanderley, Flawiá, Mirtha M., Torres, Héctor N., Docampo, Roberto, Alonso, Guillermo D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cloning, Molecular Endocytosis Gene Expression Regulation, Enzymologic Inorganic Pyrophosphatase - metabolism Lipids and Lipoproteins: Metabolism, Regulation, and Signaling Microscopy, Electron, Scanning Microscopy, Electron, Transmission Molecular Sequence Data Phenotype Phosphatidylinositol 3-Kinases - genetics Phosphatidylinositol 3-Kinases - metabolism Phosphoinositide-3 Kinase Inhibitors Protein Kinase Inhibitors - pharmacology Proton-Translocating ATPases - metabolism Saccharomyces cerevisiae - enzymology Saccharomyces cerevisiae - genetics Trypanosoma cruzi - drug effects Trypanosoma cruzi - enzymology Trypanosoma cruzi - genetics Trypanosoma cruzi - ultrastructure Water-Electrolyte Balance
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