Identification of Arx transcriptional targets in the developing basal forebrain

Mutations in the aristaless-related homeobox (ARX) gene are associated with multiple neurologic disorders in humans. Studies in mice indicate Arx plays a role in neuronal progenitor proliferation and development of the cerebral cortex, thalamus, hippocampus, striatum, and olfactory bulbs. Specific d...

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Veröffentlicht in:	Human molecular genetics 2008-12, Vol.17 (23), p.3740-3760
Hauptverfasser:	Fulp, Carl T., Cho, Ginam, Marsh, Eric D., Nasrallah, Ilya M., Labosky, Patricia A., Golden, Jeffrey A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Gene Regulatory Networks Genetics of eukaryotes. Biological and molecular evolution Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humans Intellectual Disability - genetics Intellectual Disability - metabolism Mice Mice, Inbred C57BL Mice, Transgenic Molecular and cellular biology Molecular genetics Molecular Sequence Data Prosencephalon - growth & development Prosencephalon - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcription, Genetic Transcription. Transcription factor. Splicing. Rna processing
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