Blood Pressure Control and Risk of Incident Atrial Fibrillation
Background Atrial fibrillation (AF) is a common arrhythmia that affects more than 2 million people in the United States. We sought to determine whether the risk of incident AF among patients treated for hypertension differs by the degree of blood pressure control. Methods A population-based, case–co...
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| Veröffentlicht in: | American journal of hypertension 2008-10, Vol.21 (10), p.1111-1116 |
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| creator | Thomas, M.C. Dublin, S. Kaplan, R.C. Glazer, N.L. Lumley, T. Longstreth, W.T. Smith, N.L. Psaty, B.M. Siscovick, D.S. Heckbert, S.R. |
| description | Background Atrial fibrillation (AF) is a common arrhythmia that affects more than 2 million people in the United States. We sought to determine whether the risk of incident AF among patients treated for hypertension differs by the degree of blood pressure control. Methods A population-based, case–control study of 433 patients with verified incident AF and 899 controls was conducted to investigate the relationship between average achieved systolic (SBP) and diastolic (DBP) blood pressure and risk of AF. All patients were members of an integrated health-care delivery system and were pharmacologically treated for hypertension. Medical records were reviewed to confirm the diagnosis of new onset AF and to collect information on medical conditions, health behaviors, and measured blood pressures. Average achieved SBP and DBP were calculated from the three most recent outpatient blood pressure measurements. Results Compared with the reference level of 120–129 mm Hg, for categories of average achieved SBP of |
| doi_str_mv | 10.1038/ajh.2008.248 |
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| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2577029</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1038/ajh.2008.248</oup_id><sourcerecordid>2709894461</sourcerecordid><originalsourceid>FETCH-LOGICAL-c576t-47624eb638030592a1b063a29debf69efb3cdd928513a8ffb4801123db5754983</originalsourceid><addsrcrecordid>eNqF0c1PFDEYBvDGSGQFb5zJJEa9OOvb7_YigY2wJCQIamK4NJ2ZjnSZnS7tjJH_3pLdrOjFUw_95e379EHoAMMUA1Uf7OJ2SgDUlDD1DE2wZriUhPDnaAJK81KCwLvoZUoLAGBC4BdoFyvJBeFygo5OuhCa4nN0KY3RFbPQDzF0he2b4tqnuyK0xXlf-8b1Q3E8RG-74tRX0XedHXzo99FOa7vkXm3OPfTt9NPX2by8uDw7nx1flDWXYiiZFIS5SlAFFLgmFlcgqCW6cVUrtGsrWjeNJopjalXbVkwBxoQ2FZecaUX30Mf13NVYLV1T53Wi7cwq-qWNDyZYb_6-6f2t-RF-mpxSAtF5wNvNgBjuR5cGs_SpdjlG78KYjNBcai5khq__gYswxj6HMxgIk0xxSrJ6v1Z1DClF125XwWAeezG5F_PYi8m9ZH74dP0_eFNEBm82wKbadm20-dPT1hHIIQSj2b1buzCu_vdkuZY-De7X1tp4Z3JKyc38-425mZ8IfjX7Yub0N1FLsEo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1024748532</pqid></control><display><type>article</type><title>Blood Pressure Control and Risk of Incident Atrial Fibrillation</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><creator>Thomas, M.C. ; Dublin, S. ; Kaplan, R.C. ; Glazer, N.L. ; Lumley, T. ; Longstreth, W.T. ; Smith, N.L. ; Psaty, B.M. ; Siscovick, D.S. ; Heckbert, S.R.</creator><creatorcontrib>Thomas, M.C. ; Dublin, S. ; Kaplan, R.C. ; Glazer, N.L. ; Lumley, T. ; Longstreth, W.T. ; Smith, N.L. ; Psaty, B.M. ; Siscovick, D.S. ; Heckbert, S.R.</creatorcontrib><description>Background Atrial fibrillation (AF) is a common arrhythmia that affects more than 2 million people in the United States. We sought to determine whether the risk of incident AF among patients treated for hypertension differs by the degree of blood pressure control. Methods A population-based, case–control study of 433 patients with verified incident AF and 899 controls was conducted to investigate the relationship between average achieved systolic (SBP) and diastolic (DBP) blood pressure and risk of AF. All patients were members of an integrated health-care delivery system and were pharmacologically treated for hypertension. Medical records were reviewed to confirm the diagnosis of new onset AF and to collect information on medical conditions, health behaviors, and measured blood pressures. Average achieved SBP and DBP were calculated from the three most recent outpatient blood pressure measurements. Results Compared with the reference level of 120–129 mm Hg, for categories of average achieved SBP of <120, 130–139, 140–149, 150–159, 160–169, and ≥170 mm Hg, the odds ratios (ORs; 95% confidence interval (CI)) for incident AF were 1.99 (1.10, 3.62), 1.19 (0.78, 1.81), 1.40 (0.93, 2.09), 2.02 (1.30, 3.15), 2.27 (1.31, 3.93), and 1.84 (0.89, 3.80), respectively. Based on the population attributable fraction, we estimated that, among patients with treated hypertension, 17.2% (95% CI 4.3%, 28.3%) of incident AF was attributable to an average achieved SBP ≥140 mm Hg. Conclusion Among patients treated for hypertension, uncontrolled elevated SBP and SBP <120 mm Hg were associated with an increased risk of incident AF.</description><identifier>ISSN: 0895-7061</identifier><identifier>EISSN: 1941-7225</identifier><identifier>EISSN: 1879-1905</identifier><identifier>DOI: 10.1038/ajh.2008.248</identifier><identifier>PMID: 18756257</identifier><identifier>CODEN: AJHYE6</identifier><language>eng</language><publisher>New York, NY: Oxford University Press</publisher><subject>Aged ; Antihypertensive Agents - therapeutic use ; Arterial hypertension. Arterial hypotension ; Atrial Fibrillation - epidemiology ; Atrial Fibrillation - etiology ; Atrial Fibrillation - physiopathology ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Pressure - physiology ; Blood Pressure Monitoring, Ambulatory - methods ; Cardiology. Vascular system ; Clinical manifestations. Epidemiology. Investigative techniques. Etiology ; Electrocardiography ; Female ; Follow-Up Studies ; Humans ; Hypertension - complications ; Hypertension - drug therapy ; Hypertension - physiopathology ; Incidence ; Male ; Medical sciences ; Odds Ratio ; Prognosis ; Retrospective Studies ; Risk Factors ; Washington - epidemiology</subject><ispartof>American journal of hypertension, 2008-10, Vol.21 (10), p.1111-1116</ispartof><rights>American Journal of Hypertension, Ltd. © 2008 by the American Journal of Hypertension, Ltd. 2008</rights><rights>2008 INIST-CNRS</rights><rights>Copyright Nature Publishing Group Oct 2008</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c576t-47624eb638030592a1b063a29debf69efb3cdd928513a8ffb4801123db5754983</citedby><cites>FETCH-LOGICAL-c576t-47624eb638030592a1b063a29debf69efb3cdd928513a8ffb4801123db5754983</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20702643$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18756257$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thomas, M.C.</creatorcontrib><creatorcontrib>Dublin, S.</creatorcontrib><creatorcontrib>Kaplan, R.C.</creatorcontrib><creatorcontrib>Glazer, N.L.</creatorcontrib><creatorcontrib>Lumley, T.</creatorcontrib><creatorcontrib>Longstreth, W.T.</creatorcontrib><creatorcontrib>Smith, N.L.</creatorcontrib><creatorcontrib>Psaty, B.M.</creatorcontrib><creatorcontrib>Siscovick, D.S.</creatorcontrib><creatorcontrib>Heckbert, S.R.</creatorcontrib><title>Blood Pressure Control and Risk of Incident Atrial Fibrillation</title><title>American journal of hypertension</title><addtitle>AJH</addtitle><description>Background Atrial fibrillation (AF) is a common arrhythmia that affects more than 2 million people in the United States. We sought to determine whether the risk of incident AF among patients treated for hypertension differs by the degree of blood pressure control. Methods A population-based, case–control study of 433 patients with verified incident AF and 899 controls was conducted to investigate the relationship between average achieved systolic (SBP) and diastolic (DBP) blood pressure and risk of AF. All patients were members of an integrated health-care delivery system and were pharmacologically treated for hypertension. Medical records were reviewed to confirm the diagnosis of new onset AF and to collect information on medical conditions, health behaviors, and measured blood pressures. Average achieved SBP and DBP were calculated from the three most recent outpatient blood pressure measurements. Results Compared with the reference level of 120–129 mm Hg, for categories of average achieved SBP of <120, 130–139, 140–149, 150–159, 160–169, and ≥170 mm Hg, the odds ratios (ORs; 95% confidence interval (CI)) for incident AF were 1.99 (1.10, 3.62), 1.19 (0.78, 1.81), 1.40 (0.93, 2.09), 2.02 (1.30, 3.15), 2.27 (1.31, 3.93), and 1.84 (0.89, 3.80), respectively. Based on the population attributable fraction, we estimated that, among patients with treated hypertension, 17.2% (95% CI 4.3%, 28.3%) of incident AF was attributable to an average achieved SBP ≥140 mm Hg. Conclusion Among patients treated for hypertension, uncontrolled elevated SBP and SBP <120 mm Hg were associated with an increased risk of incident AF.</description><subject>Aged</subject><subject>Antihypertensive Agents - therapeutic use</subject><subject>Arterial hypertension. Arterial hypotension</subject><subject>Atrial Fibrillation - epidemiology</subject><subject>Atrial Fibrillation - etiology</subject><subject>Atrial Fibrillation - physiopathology</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Pressure - physiology</subject><subject>Blood Pressure Monitoring, Ambulatory - methods</subject><subject>Cardiology. Vascular system</subject><subject>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Hypertension - complications</subject><subject>Hypertension - drug therapy</subject><subject>Hypertension - physiopathology</subject><subject>Incidence</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Odds Ratio</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Washington - epidemiology</subject><issn>0895-7061</issn><issn>1941-7225</issn><issn>1879-1905</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0c1PFDEYBvDGSGQFb5zJJEa9OOvb7_YigY2wJCQIamK4NJ2ZjnSZnS7tjJH_3pLdrOjFUw_95e379EHoAMMUA1Uf7OJ2SgDUlDD1DE2wZriUhPDnaAJK81KCwLvoZUoLAGBC4BdoFyvJBeFygo5OuhCa4nN0KY3RFbPQDzF0he2b4tqnuyK0xXlf-8b1Q3E8RG-74tRX0XedHXzo99FOa7vkXm3OPfTt9NPX2by8uDw7nx1flDWXYiiZFIS5SlAFFLgmFlcgqCW6cVUrtGsrWjeNJopjalXbVkwBxoQ2FZecaUX30Mf13NVYLV1T53Wi7cwq-qWNDyZYb_6-6f2t-RF-mpxSAtF5wNvNgBjuR5cGs_SpdjlG78KYjNBcai5khq__gYswxj6HMxgIk0xxSrJ6v1Z1DClF125XwWAeezG5F_PYi8m9ZH74dP0_eFNEBm82wKbadm20-dPT1hHIIQSj2b1buzCu_vdkuZY-De7X1tp4Z3JKyc38-425mZ8IfjX7Yub0N1FLsEo</recordid><startdate>20081001</startdate><enddate>20081001</enddate><creator>Thomas, M.C.</creator><creator>Dublin, S.</creator><creator>Kaplan, R.C.</creator><creator>Glazer, N.L.</creator><creator>Lumley, T.</creator><creator>Longstreth, W.T.</creator><creator>Smith, N.L.</creator><creator>Psaty, B.M.</creator><creator>Siscovick, D.S.</creator><creator>Heckbert, S.R.</creator><general>Oxford University Press</general><general>Elsevier Science</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20081001</creationdate><title>Blood Pressure Control and Risk of Incident Atrial Fibrillation</title><author>Thomas, M.C. ; Dublin, S. ; Kaplan, R.C. ; Glazer, N.L. ; Lumley, T. ; Longstreth, W.T. ; Smith, N.L. ; Psaty, B.M. ; Siscovick, D.S. ; Heckbert, S.R.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c576t-47624eb638030592a1b063a29debf69efb3cdd928513a8ffb4801123db5754983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Aged</topic><topic>Antihypertensive Agents - therapeutic use</topic><topic>Arterial hypertension. Arterial hypotension</topic><topic>Atrial Fibrillation - epidemiology</topic><topic>Atrial Fibrillation - etiology</topic><topic>Atrial Fibrillation - physiopathology</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Pressure - physiology</topic><topic>Blood Pressure Monitoring, Ambulatory - methods</topic><topic>Cardiology. Vascular system</topic><topic>Clinical manifestations. Epidemiology. Investigative techniques. Etiology</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Hypertension - complications</topic><topic>Hypertension - drug therapy</topic><topic>Hypertension - physiopathology</topic><topic>Incidence</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Odds Ratio</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Washington - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thomas, M.C.</creatorcontrib><creatorcontrib>Dublin, S.</creatorcontrib><creatorcontrib>Kaplan, R.C.</creatorcontrib><creatorcontrib>Glazer, N.L.</creatorcontrib><creatorcontrib>Lumley, T.</creatorcontrib><creatorcontrib>Longstreth, W.T.</creatorcontrib><creatorcontrib>Smith, N.L.</creatorcontrib><creatorcontrib>Psaty, B.M.</creatorcontrib><creatorcontrib>Siscovick, D.S.</creatorcontrib><creatorcontrib>Heckbert, S.R.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>American journal of hypertension</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thomas, M.C.</au><au>Dublin, S.</au><au>Kaplan, R.C.</au><au>Glazer, N.L.</au><au>Lumley, T.</au><au>Longstreth, W.T.</au><au>Smith, N.L.</au><au>Psaty, B.M.</au><au>Siscovick, D.S.</au><au>Heckbert, S.R.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Blood Pressure Control and Risk of Incident Atrial Fibrillation</atitle><jtitle>American journal of hypertension</jtitle><addtitle>AJH</addtitle><date>2008-10-01</date><risdate>2008</risdate><volume>21</volume><issue>10</issue><spage>1111</spage><epage>1116</epage><pages>1111-1116</pages><issn>0895-7061</issn><eissn>1941-7225</eissn><eissn>1879-1905</eissn><coden>AJHYE6</coden><abstract>Background Atrial fibrillation (AF) is a common arrhythmia that affects more than 2 million people in the United States. We sought to determine whether the risk of incident AF among patients treated for hypertension differs by the degree of blood pressure control. Methods A population-based, case–control study of 433 patients with verified incident AF and 899 controls was conducted to investigate the relationship between average achieved systolic (SBP) and diastolic (DBP) blood pressure and risk of AF. All patients were members of an integrated health-care delivery system and were pharmacologically treated for hypertension. Medical records were reviewed to confirm the diagnosis of new onset AF and to collect information on medical conditions, health behaviors, and measured blood pressures. Average achieved SBP and DBP were calculated from the three most recent outpatient blood pressure measurements. Results Compared with the reference level of 120–129 mm Hg, for categories of average achieved SBP of <120, 130–139, 140–149, 150–159, 160–169, and ≥170 mm Hg, the odds ratios (ORs; 95% confidence interval (CI)) for incident AF were 1.99 (1.10, 3.62), 1.19 (0.78, 1.81), 1.40 (0.93, 2.09), 2.02 (1.30, 3.15), 2.27 (1.31, 3.93), and 1.84 (0.89, 3.80), respectively. Based on the population attributable fraction, we estimated that, among patients with treated hypertension, 17.2% (95% CI 4.3%, 28.3%) of incident AF was attributable to an average achieved SBP ≥140 mm Hg. Conclusion Among patients treated for hypertension, uncontrolled elevated SBP and SBP <120 mm Hg were associated with an increased risk of incident AF.</abstract><cop>New York, NY</cop><pub>Oxford University Press</pub><pmid>18756257</pmid><doi>10.1038/ajh.2008.248</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Aged Antihypertensive Agents - therapeutic use Arterial hypertension. Arterial hypotension Atrial Fibrillation - epidemiology Atrial Fibrillation - etiology Atrial Fibrillation - physiopathology Biological and medical sciences Blood and lymphatic vessels Blood Pressure - physiology Blood Pressure Monitoring, Ambulatory - methods Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Electrocardiography Female Follow-Up Studies Humans Hypertension - complications Hypertension - drug therapy Hypertension - physiopathology Incidence Male Medical sciences Odds Ratio Prognosis Retrospective Studies Risk Factors Washington - epidemiology |
| title | Blood Pressure Control and Risk of Incident Atrial Fibrillation |
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