Human infrapatellar fat pad-derived stem cells express the pericyte marker 3G5 and show enhanced chondrogenesis after expansion in fibroblast growth factor-2

Infrapatellar fat pad (IPFP) is a possible source of stem cells for the repair of articular cartilage defects. In this study, adherent proliferative cells were isolated from digests of IPFP tissue. The effects of the expansion of these cells in fibroblast growth factor-2 (FGF-2) were tested on their...

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Veröffentlicht in:	Arthritis research & therapy 2008-01, Vol.10 (4), p.R74-R74, Article R74
Hauptverfasser:	Khan, Wasim S, Tew, Simon R, Adesida, Adetola B, Hardingham, Timothy E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - cytology Adipose Tissue - drug effects Adipose Tissue - metabolism Antibodies, Monoclonal - metabolism Care and treatment Cell Differentiation - drug effects Cell Proliferation - drug effects Cell- and Tissue-Based Therapy Cells, Cultured Chondrogenesis - drug effects Connective tissue diseases Fibroblast Growth Factor 2 - pharmacology Fibroblast growth factors Growth Substances - pharmacology Humans Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mesenchymal Stromal Cells - metabolism Patella - cytology Patella - drug effects Patella - metabolism Pericytes - cytology Physiological aspects Rheumatic Diseases - therapy Risk factors Stem cells
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