Structures of invisible, excited protein states by relaxation dispersion NMR spectroscopy

Molecular function is often predicated on excursions between ground states and higher energy conformers that can play important roles in ligand binding, molecular recognition, enzyme catalysis, and protein folding. The tools of structural biology enable a detailed characterization of ground state st...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2008-08, Vol.105 (33), p.11766-11771
Hauptverfasser: Vallurupalli, Pramodh, Hansen, D. Flemming, Kay, Lewis E
Format: Artikel
Sprache:eng
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