Chronic LPS Inhalation Causes Emphysema-Like Changes in Mouse Lung that Are Associated with Apoptosis

Lipopolysaccharide (LPS) is ubiquitous in the environment. Recent epidemiologic data suggest that occupational exposure to inhaled LPS can contribute to the progression of chronic obstructive pulmonary disease. To address the hypothesis that inhaled LPS can cause emphysema-like changes in mouse pulm...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of respiratory cell and molecular biology 2008-11, Vol.39 (5), p.584-590
Hauptverfasser:	Brass, David M, Hollingsworth, John W, Cinque, Mark, Li, Zhouwei, Potts, Erin, Toloza, Eric, Foster, William M, Schwartz, David A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Gene Expression Regulation - drug effects Inhalation Lipopolysaccharides - administration & dosage Male Matrix Metalloproteinase 9 - deficiency Matrix Metalloproteinase 9 - genetics Matrix Metalloproteinase 9 - metabolism Mice Mice, Knockout Neutrophils - metabolism Procollagen - genetics Procollagen - metabolism Pulmonary Emphysema - chemically induced Pulmonary Emphysema - pathology Time Factors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!