Mouse model of focal cerebral ischemia using endothelin-1

Intracerebral injection of the vasoconstrictor peptide, endothelin-1 (ET-1), has been used as a method to induce focal ischemia in rats. The relative technical simplicity of this model makes it attractive for use in mice. However, the effect of ET-1 on mouse brains has not been firmly established. I...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroscience methods 2008-08, Vol.173 (2), p.286-290
Hauptverfasser:	Horie, Nobutaka, Maag, Anne-Lise, Hamilton, Scott A., Shichinohe, Hideo, Bliss, Tonya M., Steinberg, Gary K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Infarction - chemically induced Brain Infarction - pathology Brain Infarction - physiopathology Brain Ischemia - chemically induced Brain Ischemia - pathology Brain Ischemia - physiopathology Carotid Artery Diseases - etiology Carotid Artery Diseases - physiopathology Cerebral Arteries - drug effects Cerebral Arteries - pathology Cerebral Arteries - physiopathology Disease Models, Animal Endothelial nitric oxide Endothelin-1 Endothelin-1 - pharmacology Enzyme Inhibitors - pharmacology Focal ischemia Male Mice Mice, Inbred C57BL Mice, SCID Mouse NG-Nitroarginine Methyl Ester - pharmacology Nitric Oxide Synthase Type III - antagonists & inhibitors Rats Rats, Sprague-Dawley Receptor Species Specificity Vasoconstriction - drug effects Vasoconstriction - physiology Vasoconstrictor Agents - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!