The Crystal Structure of the BAR Domain from Human Bin1/Amphiphysin II and Its Implications for Molecular Recognition

BAR domains are found in proteins that bind and remodel membranes and participate in cytoskeletal and nuclear processes. Here, we report the crystal structure of the BAR domain from the human Bin1 protein at 2.0 Å resolution. Both the quaternary and tertiary architectures of the homodimeric Bin1BAR...

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Veröffentlicht in:Biochemistry (Easton) 2006-10, Vol.45 (43), p.12917-12928
Hauptverfasser: Casal, Eva, Federici, Luca, Zhang, Wei, Fernandez-Recio, Juan, Priego, Eva-Maria, Miguel, Ricardo Nuñez, DuHadaway, James B, Prendergast, George C, Luisi, Ben F, Laue, Ernest D
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Sprache:eng
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