Macaques vaccinated with live-attenuated SIV control replication of heterologous virus

An effective AIDS vaccine will need to protect against globally diverse isolates of HIV. To address this issue in macaques, we administered a live-attenuated simian immunodeficiency virus (SIV) vaccine and challenged with a highly pathogenic heterologous isolate. Vaccinees reduced viral replication...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of experimental medicine 2008-10, Vol.205 (11), p.2537-2550
Hauptverfasser:	Reynolds, Matthew R, Weiler, Andrea M, Weisgrau, Kim L, Piaskowski, Shari M, Furlott, Jessica R, Weinfurter, Jason T, Kaizu, Masahiko, Soma, Taeko, León, Enrique J, MacNair, Caitlin, Leaman, Dan P, Zwick, Michael B, Gostick, Emma, Musani, Solomon K, Price, David A, Friedrich, Thomas C, Rakasz, Eva G, Wilson, Nancy A, McDermott, Adrian B, Boyle, Rosanne, Allison, David B, Burton, Dennis R, Koff, Wayne C, Watkins, David I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence CD8-Positive T-Lymphocytes - immunology DNA Primers - genetics Genetic Variation Macaca Molecular Sequence Data Reverse Transcriptase Polymerase Chain Reaction RNA, Viral - genetics SAIDS Vaccines - genetics SAIDS Vaccines - immunology Sequence Analysis, RNA Simian Acquired Immunodeficiency Syndrome - prevention & control Simian Immunodeficiency Virus - genetics Simian Immunodeficiency Virus - immunology Simian Immunodeficiency Virus - physiology Vaccines, Attenuated - genetics Vaccines, Attenuated - immunology Virus Replication - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!