IDDM2 and the polymorphism of the human tyrosine hydroxylase (hTH) gene in African Americans with type-1 diabetes

In this study, we investigate the polymorphic microsatellite repeat (TCAT)n, in the insulin gene region that has been associated with susceptibility to type-1 diabetes in some Caucasian populations. The microsatellite repeat polymorphism begins at base pair 1,170 in intron 1 of the hTH gene, which i...

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Veröffentlicht in:	Journal of the National Medical Association 2004-08, Vol.96 (8), p.1042-1046
Hauptverfasser:	BERKA, Noureddine, NUNLEE-BLAND, Gail, ERABHAOUI, Elhajja, BELMAMOUN, Maher, DUNSTON, Georgia M
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans - genetics Alleles Biological and medical sciences Diabetes Mellitus, Type 1 - genetics Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance General aspects Humans Insulin - genetics Medical sciences Microsatellite Repeats Polymorphism, Genetic - genetics Tyrosine 3-Monooxygenase - genetics
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