Telomere maintenance and dysfunction predict recurrence in paediatric ependymoma

We have recently described the enzymatic subunit of telomerase (hTERT) as an important prognostic marker for paediatric ependymoma. Because of the lack of good, representative pre-clinical models for ependymoma, we took advantage of our large cohort of ependymoma patients, some with multiple recurre...

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Veröffentlicht in:	British journal of cancer 2008-10, Vol.99 (7), p.1129-1135
Hauptverfasser:	Tabori, U, Wong, V, Ma, J, Shago, M, Alon, N, Rutka, J, Bouffet, E, Bartels, U, Malkin, D, Hawkins, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biology Biomedical and Life Sciences Biomedicine Brain cancer Cancer Research Cancer therapies Central Nervous System Neoplasms - genetics Central Nervous System Neoplasms - pathology Central Nervous System Neoplasms - therapy Chemotherapy Child Cohort Studies DNA damage Drug Resistance Ependymoma - genetics Ependymoma - pathology Ependymoma - therapy Epidemiology Humans Immunohistochemistry Medical prognosis Medical research Medical sciences Metastasis Molecular Diagnostics Molecular Medicine Neurology Oncology Pathology Pediatrics Prognosis Radiation Recurrence Survival analysis Telomerase Telomere Tumors Tumors of the nervous system. Phacomatoses Yeast
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