Role of Inflammation in the Development of Renal Damage and Dysfunction in Angiotensin II–Induced Hypertension

Angiotensin II (Ang II)–induced hypertension is associated with an inflammatory response that may contribute to the development of target organ damage. We tested the hypothesis that, in Ang II–induced hypertension, CC chemokine receptor 2 (CCR2) activation plays an important role in the development...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2008-08, Vol.52 (2), p.256-263
Hauptverfasser:	Liao, Tang-Dong, Yang, Xiao-Ping, Liu, Yun-He, Shesely, Edward G, Cavasin, Maria A, Kuziel, William A, Pagano, Patrick J, Carretero, Oscar A
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuminuria - diagnosis Angiotensin II Animals Blotting, Western Cell Movement Cell Proliferation Disease Models, Animal Glomerular Filtration Rate Hypertension - chemically induced Hypertension - complications Hypertension - physiopathology Immunohistochemistry Inflammation - physiopathology Macrophages - cytology Male Mice Mice, Inbred C57BL Mice, Knockout Nephrosclerosis - etiology Nephrosclerosis - pathology Probability Random Allocation Reactive Oxygen Species - analysis Receptors, Chemokine - analysis Reference Values Sensitivity and Specificity
Online-Zugang:	Volltext
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