Iron and contact with host cells induce expression of adhesins on surface of Trichomonas vaginalis

Summary The proteins AP65, AP51, AP33 and AP23 synthesized by Trichomonas vaginalis organisms in high iron play a role in adherence. Multigene families encode enzymes of the hydrogenosome organelles, which have identity to adhesins. This fact raises questions regarding the compartmentalization of th...

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Veröffentlicht in:	Molecular microbiology 2003-03, Vol.47 (5), p.1207-1224
Hauptverfasser:	Garcia, Ana F., Chang, Te‐Hung, Benchimol, Marlene, Klumpp, David Jichael, Lehker, Michael W., Alderete, John F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal - immunology Antibodies, Protozoan - immunology Antigens, Protozoan - biosynthesis Antigens, Protozoan - genetics Antigens, Protozoan - immunology Antigens, Surface - biosynthesis Antigens, Surface - genetics Antigens, Surface - immunology Cell Adhesion Cell Adhesion Molecules - biosynthesis Cell Adhesion Molecules - genetics Cell Line, Transformed Culture Media - pharmacology Epithelial Cells - parasitology Epitopes - immunology Female Gene Expression Regulation - drug effects Iron - pharmacology Membrane Proteins - biosynthesis Membrane Proteins - genetics Molecular Sequence Data Multigene Family Organelles - enzymology Protozoan Proteins - biosynthesis Protozoan Proteins - genetics Protozoan Proteins - immunology Rabbits Trichomonas vaginalis - genetics Trichomonas vaginalis - metabolism Trichomonas vaginalis - physiology Ureter - cytology Vagina - cytology
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