Brain-Derived Neurotrophic Factor and Obesity in the WAGR Syndrome

This study examined genotype and body-mass index in patients with the Wilms' tumor, aniridia, genitourinary anomalies, and mental retardation (WAGR) syndrome. The related genes WT1 and PAX6 are on chromosome 11p13, centromeric to brain-derived neurotrophic factor ( BDNF ), an important gene in...

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Veröffentlicht in:	The New England journal of medicine 2008-08, Vol.359 (9), p.918-927
Hauptverfasser:	Han, Joan C, Liu, Qing-Rong, Jones, MaryPat, Levinn, Rebecca L, Menzie, Carolyn M, Jefferson-George, Kyra S, Adler-Wailes, Diane C, Sanford, Ethan L, Lacbawan, Felicitas L, Uhl, George R, Rennert, Owen M, Yanovski, Jack A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Body Mass Index Brain-derived neurotrophic factor Brain-Derived Neurotrophic Factor - blood Brain-Derived Neurotrophic Factor - genetics Child Child, Preschool Children & youth Chromosome Mapping Chromosomes, Human, Pair 11 Consent Energy Metabolism - genetics Female Gene Deletion General aspects Genotype Haplotypes Homeostasis Homeostasis - genetics Humans Hyperphagia - etiology Hypotheses Male Medical sciences Metabolic diseases Microsatellite Repeats Nucleic Acid Hybridization Obesity Obesity - genetics Oligonucleotide Array Sequence Analysis Pain Measurement Studies Surveys and Questionnaires WAGR Syndrome - blood WAGR Syndrome - complications WAGR Syndrome - genetics
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