Ethanol-BDNF interactions: still more questions than answers

Brain-derived neurotrophic factor (BDNF) has emerged as a regulator of development, plasticity and, recently, addiction. Decreased neurotrophic activity may be involved in ethanol-induced neurodegeneration in the adult brain and in the etiology of alcohol-related neurodevelopmental disorders. This c...

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Veröffentlicht in:	Pharmacology & therapeutics (Oxford) 2008-04, Vol.118 (1), p.36-57
1. Verfasser:	Davis, Margaret I
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism - drug therapy Alcoholism - physiopathology Animals Brain-Derived Neurotrophic Factor - drug effects Brain-Derived Neurotrophic Factor - metabolism Central Nervous System Depressants - adverse effects Disease Models, Animal Drug Delivery Systems Ethanol - adverse effects Female Fetal Alcohol Spectrum Disorders - physiopathology Humans Nerve Degeneration - chemically induced Nerve Degeneration - physiopathology Pregnancy Receptor, trkB - drug effects Receptor, trkB - metabolism Signal Transduction - drug effects
Online-Zugang:	Volltext
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