Upregulation of vascular endothelial growth factor isoform VEGF-164 and receptors (VEGFR-2, Npn-1, and Npn-2) in rats with cyclophosphamide-induced cystitis

Departments of 1 Neurology and 2 Anatomy, University of Vermont College of Medicine, Burlington, Vermont Submitted 13 May 2008 ; accepted in final form 11 July 2008 Regulation of the VEGF-VEGF receptor system was examined in the urinary bladder after acute (2–48 h) and chronic (10 days) cyclophospha...

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Veröffentlicht in:	American Journal of Physiology - Renal Physiology 2008-09, Vol.295 (3), p.F826-F836
Hauptverfasser:	Cheppudira, Bopaiah P, Girard, Beatrice M, Malley, Susan E, Schutz, Kristin C, May, Victor, Vizzard, Margaret A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents, Alkylating - pharmacology Bladder Cell growth Cells Cyclophosphamide - pharmacology Cystitis - chemically induced Cystitis - metabolism Enzyme-Linked Immunosorbent Assay Female Immunohistochemistry Membrane Proteins - genetics Muscle, Smooth - metabolism Nerve Growth Factor - metabolism Neuropilins - metabolism Promoter Regions, Genetic Protein Isoforms - metabolism Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Rodents Up-Regulation Urinary Bladder - blood supply Urinary Bladder - drug effects Urinary Bladder - metabolism Urinary tract diseases Urogenital system Uroplakin II Urothelium - metabolism Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-2 - metabolism
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