Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread
Between 31 July and 6 October 1979, 34 cases of Ebola virus disease (22 of which were fatal) occurred among five families in a rural district of southern Sudan; the disease was introduced into four of the families from a local hospital. Chains of secondary spread within the family units, accounting...
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| Veröffentlicht in: | Bulletin of the World Health Organization 1983, Vol.61 (6), p.997-1003 |
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| creator | BARON, R. C MCCORMICK, J. B ZUBEIR, O. A |
| description | Between 31 July and 6 October 1979, 34 cases of Ebola virus disease (22 of which were fatal) occurred among five families in a rural district of southern Sudan; the disease was introduced into four of the families from a local hospital. Chains of secondary spread within the family units, accounting for 29 cases resulted from direct physical contact with an infected person. Among all persons with such contact in the family setting, those who provided nursing care had a 5.1-fold increased risk of infection, emphasizing the importance of intimate contact in the spread of this disease. The absence of illness among persons who were exposed to cases in confined spaces, but without physical contact, confirmed previous impressions that there is no risk of airborne transmission. While the ecology of Ebola virus is unknown, the presence of anti-Ebola antibodies in the sera of 18% of persons who were unassociated with the outbreak suggests that the region is an endemic focus of Ebola virus activity. |
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While the ecology of Ebola virus is unknown, the presence of anti-Ebola antibodies in the sera of 18% of persons who were unassociated with the outbreak suggests that the region is an endemic focus of Ebola virus activity.</description><identifier>ISSN: 0042-9686</identifier><identifier>EISSN: 1564-0604</identifier><identifier>PMID: 6370486</identifier><identifier>CODEN: BWHOA6</identifier><language>eng</language><publisher>Genève: Organisation mondiale de la santé</publisher><subject>Adolescent ; Adult ; Antibodies, Viral - immunology ; Biological and medical sciences ; Child ; Cross Infection ; Disease Outbreaks ; Ebolavirus - immunology ; Ebolavirus - isolation & purification ; Female ; Fluorescent Antibody Technique ; Hemorrhagic Fevers, Viral - genetics ; Hemorrhagic Fevers, Viral - immunology ; Hemorrhagic Fevers, Viral - transmission ; Human viral diseases ; Humans ; Infectious diseases ; Male ; Marburg disease, ebola disease ; Medical sciences ; Middle Aged ; Risk ; Rural Population ; Sudan ; Tropical medicine ; Tropical viral diseases ; Viral diseases</subject><ispartof>Bulletin of the World Health Organization, 1983, Vol.61 (6), p.997-1003</ispartof><rights>1984 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536233/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2536233/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,4009,53770,53772</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=9461938$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6370486$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BARON, R. C</creatorcontrib><creatorcontrib>MCCORMICK, J. B</creatorcontrib><creatorcontrib>ZUBEIR, O. A</creatorcontrib><title>Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread</title><title>Bulletin of the World Health Organization</title><addtitle>Bull World Health Organ</addtitle><description>Between 31 July and 6 October 1979, 34 cases of Ebola virus disease (22 of which were fatal) occurred among five families in a rural district of southern Sudan; the disease was introduced into four of the families from a local hospital. Chains of secondary spread within the family units, accounting for 29 cases resulted from direct physical contact with an infected person. Among all persons with such contact in the family setting, those who provided nursing care had a 5.1-fold increased risk of infection, emphasizing the importance of intimate contact in the spread of this disease. The absence of illness among persons who were exposed to cases in confined spaces, but without physical contact, confirmed previous impressions that there is no risk of airborne transmission. While the ecology of Ebola virus is unknown, the presence of anti-Ebola antibodies in the sera of 18% of persons who were unassociated with the outbreak suggests that the region is an endemic focus of Ebola virus activity.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antibodies, Viral - immunology</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Cross Infection</subject><subject>Disease Outbreaks</subject><subject>Ebolavirus - immunology</subject><subject>Ebolavirus - isolation & purification</subject><subject>Female</subject><subject>Fluorescent Antibody Technique</subject><subject>Hemorrhagic Fevers, Viral - genetics</subject><subject>Hemorrhagic Fevers, Viral - immunology</subject><subject>Hemorrhagic Fevers, Viral - transmission</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Marburg disease, ebola disease</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Risk</subject><subject>Rural Population</subject><subject>Sudan</subject><subject>Tropical medicine</subject><subject>Tropical viral diseases</subject><subject>Viral diseases</subject><issn>0042-9686</issn><issn>1564-0604</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkE1LxDAQhoMo67r6E4QexFshTdI08SDIsn7AgocVr2WapG4kTWrSLvjv7eKy6Fzm8Dy87zAnaF6UnOWYY3aK5hgzkksu-Dm6SOkTTyMZnqEZpxVmgs_R-6oJDrKdjWPKtE0Gksmsz1IYh62JPtuMGvxdtg2ptwO4vZNMZz0MNvgMvJ7sIUILnXV24qmPBvQlOmvBJXN12Au0eVy9LZ_z9evTy_JhnfdE4iGvWkm5lpgpAaVsG6JFUUDZADMUM14RrZVWTUtERQgFbVgrjdKSq0kndIHuf1P7semMVmZ_iav7aDuI33UAW_8n3m7rj7CrSUk5oXQKuD0ExPA1mjTUnU3KOAfehDHVAgshGNuL13-bjhWHP0785sAhKXBtBK9sOmqS8UJSQX8AdW1_tw</recordid><startdate>1983</startdate><enddate>1983</enddate><creator>BARON, R. C</creator><creator>MCCORMICK, J. B</creator><creator>ZUBEIR, O. A</creator><general>Organisation mondiale de la santé</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>1983</creationdate><title>Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread</title><author>BARON, R. C ; MCCORMICK, J. B ; ZUBEIR, O. A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p290t-7f936d904c8a59fb2d811a5ba4e304672ddcdcbf287223ade4f9ecd96ca5923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Antibodies, Viral - immunology</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Cross Infection</topic><topic>Disease Outbreaks</topic><topic>Ebolavirus - immunology</topic><topic>Ebolavirus - isolation & purification</topic><topic>Female</topic><topic>Fluorescent Antibody Technique</topic><topic>Hemorrhagic Fevers, Viral - genetics</topic><topic>Hemorrhagic Fevers, Viral - immunology</topic><topic>Hemorrhagic Fevers, Viral - transmission</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Marburg disease, ebola disease</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Risk</topic><topic>Rural Population</topic><topic>Sudan</topic><topic>Tropical medicine</topic><topic>Tropical viral diseases</topic><topic>Viral diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BARON, R. C</creatorcontrib><creatorcontrib>MCCORMICK, J. B</creatorcontrib><creatorcontrib>ZUBEIR, O. A</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Bulletin of the World Health Organization</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BARON, R. C</au><au>MCCORMICK, J. B</au><au>ZUBEIR, O. A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread</atitle><jtitle>Bulletin of the World Health Organization</jtitle><addtitle>Bull World Health Organ</addtitle><date>1983</date><risdate>1983</risdate><volume>61</volume><issue>6</issue><spage>997</spage><epage>1003</epage><pages>997-1003</pages><issn>0042-9686</issn><eissn>1564-0604</eissn><coden>BWHOA6</coden><abstract>Between 31 July and 6 October 1979, 34 cases of Ebola virus disease (22 of which were fatal) occurred among five families in a rural district of southern Sudan; the disease was introduced into four of the families from a local hospital. Chains of secondary spread within the family units, accounting for 29 cases resulted from direct physical contact with an infected person. Among all persons with such contact in the family setting, those who provided nursing care had a 5.1-fold increased risk of infection, emphasizing the importance of intimate contact in the spread of this disease. The absence of illness among persons who were exposed to cases in confined spaces, but without physical contact, confirmed previous impressions that there is no risk of airborne transmission. While the ecology of Ebola virus is unknown, the presence of anti-Ebola antibodies in the sera of 18% of persons who were unassociated with the outbreak suggests that the region is an endemic focus of Ebola virus activity.</abstract><cop>Genève</cop><pub>Organisation mondiale de la santé</pub><pmid>6370486</pmid><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0042-9686 |
| ispartof | Bulletin of the World Health Organization, 1983, Vol.61 (6), p.997-1003 |
| issn | 0042-9686 1564-0604 |
| language | eng |
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| source | PubMed (Medline); MEDLINE; EZB Electronic Journals Library |
| subjects | Adolescent Adult Antibodies, Viral - immunology Biological and medical sciences Child Cross Infection Disease Outbreaks Ebolavirus - immunology Ebolavirus - isolation & purification Female Fluorescent Antibody Technique Hemorrhagic Fevers, Viral - genetics Hemorrhagic Fevers, Viral - immunology Hemorrhagic Fevers, Viral - transmission Human viral diseases Humans Infectious diseases Male Marburg disease, ebola disease Medical sciences Middle Aged Risk Rural Population Sudan Tropical medicine Tropical viral diseases Viral diseases |
| title | Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread |
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