A Tetrafluorophenyl Activated Ester Self-Assembled Monolayer for the Immobilization of Amine-Modified Oligonucleotides

A tetrafluorophenyl (TFP) ester-terminated self-assembled monolayer (SAM) for the fabrication of DNA arrays on gold surfaces is described. Activated ester SAMs are desirable for biomolecule array fabrication because they readily react with amine-containing molecules to form a stable amide linkage. N...

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Veröffentlicht in:	Langmuir 2008-01, Vol.24 (1), p.69-75
Hauptverfasser:	Lockett, Matthew R, Phillips, Margaret F, Jarecki, Jessica L, Peelen, Dora, Smith, Lloyd M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amines - chemistry Base Sequence Biosensing Techniques - methods Chemistry Colloidal state and disperse state Exact sciences and technology General and physical chemistry Gold - chemistry Hydrocarbons, Fluorinated - chemistry Hydrogen-Ion Concentration Hydrolysis Hydrophobic and Hydrophilic Interactions Oligonucleotide Array Sequence Analysis Oligonucleotides - chemistry Spectroscopy, Fourier Transform Infrared Succinimides - chemistry Surface physical chemistry Surface Properties
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