Regulation of telomere length by checkpoint genes in Schizosaccharomyces pombe

We have studied telomere length in Schizosaccharomyces pombe strains carrying mutations affecting cell cycle checkpoints, DNA repair, and regulation of the Cdc2 protein kinase. Telomere shortening was found in rad1, rad3, rad17, and rad26 mutants. Telomere lengths in previously characterized rad1 mu...

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Veröffentlicht in:	Molecular biology of the cell 1998-03, Vol.9 (3), p.611-621
Hauptverfasser:	Dahlen, M, Olsson, T, Kanter-Smoler, G, Ramne, A, Sunnerhagen, P
Format:	Artikel
Sprache:	eng
Schlagworte:	CDC2 Protein Kinase - genetics Cell Cycle - genetics Chromosomes, Fungal - genetics Chromosomes, Fungal - ultrastructure DNA Repair - genetics DNA Repair Enzymes DNA Replication - genetics DNA, Fungal - biosynthesis DNA, Fungal - genetics DNA-Binding Proteins Endonucleases - genetics Endonucleases - metabolism Fungal Proteins - genetics Fungal Proteins - metabolism Genes, Fungal Kinetics Mutation Potassium Channels - genetics Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae - ultrastructure Saccharomyces cerevisiae Proteins Schizosaccharomyces - genetics Schizosaccharomyces - metabolism Schizosaccharomyces - ultrastructure Schizosaccharomyces pombe Proteins Telomere - genetics Telomere - ultrastructure Temperature
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