A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

The genetic basis of bipolar disorder has long been thought to be complex, with the potential involvement of multiple genes, but methods to analyze populations with respect to this complexity have only recently become available. We have carried out a genome-wide association study of bipolar disorder...

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Veröffentlicht in:	Molecular psychiatry 2008-02, Vol.13 (2), p.197-207
Hauptverfasser:	Baum, A E, Akula, N, Cabanero, M, Cardona, I, Corona, W, Klemens, B, Schulze, T G, Cichon, S, Rietschel, M, Nöthen, M M, Georgi, A, Schumacher, J, Schwarz, M, Abou Jamra, R, Höfels, S, Propping, P, Satagopan, J, Detera-Wadleigh, S D, Hardy, J, McMahon, F J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Anxiety disorders Behavioral Sciences Biological and medical sciences Biological Psychology Bipolar disorder Bipolar Disorder - etiology Bipolar Disorder - genetics Bipolar disorders Case-Control Studies Deoxyribonucleic acid Diacylglycerol Diacylglycerol kinase Diacylglycerol Kinase - genetics DNA Epidemiology Etiology Europe Female Genes Genetic aspects Genetic Predisposition to Disease Genetic testing Genetics Genome Genome-wide association studies Genomes Genomics Genotyping Health aspects Humans Independent sample Inositol Kinases Linkage Disequilibrium Lithium Male Mania Medical sciences Medicine Medicine & Public Health Membrane proteins Mental health Models, Biological Mood disorders Neurosciences original-article Pharmacotherapy Polymorphism, Single Nucleotide Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Random Allocation Single nucleotide polymorphisms Single-nucleotide polymorphism
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