Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection

Viral infections often induce potent CD8 T cell responses that play a key role in antiviral immunity. After viral clearance, the vast majority of the expanded CD8 T cells undergo apoptosis, leaving behind a stable number of memory cells. The relationship between the CD8 T cells that clear the acute...

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Veröffentlicht in:	The Journal of experimental medicine 1998-07, Vol.188 (1), p.71-82
Hauptverfasser:	Sourdive, D J, Murali-Krishna, K, Altman, J D, Zajac, A J, Whitmire, J K, Pannetier, C, Kourilsky, P, Evavold, B, Sette, A, Ahmed, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals CD8-Positive T-Lymphocytes - immunology Complementarity Determining Regions Disease Models, Animal Immunoglobulin alpha-Chains - immunology Immunologic Memory - immunology Infections - virology Lymphocytic choriomeningitis virus - immunology Major Histocompatibility Complex - immunology Mice Mice, Inbred BALB C Receptors, Antigen, T-Cell - immunology T-Lymphocytes, Cytotoxic - immunology
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