The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

The complex pathophysiology of lung allergic inflammation and bronchial hyperresponsiveness (BHR) that characterize asthma is achieved by the regulated accumulation and activation of different leukocyte subsets in the lung. The development and maintenance of these processes correlate with the coordi...

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Veröffentlicht in:	The Journal of experimental medicine 1998-07, Vol.188 (1), p.157-167
Hauptverfasser:	Gonzalo, J A, Lloyd, C M, Wen, D, Albar, J P, Wells, T N, Proudfoot, A, Martinez-A, C, Dorf, M, Bjerke, T, Coyle, A J, Gutierrez-Ramos, J C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - immunology Asthma - physiopathology Chemokine CCL11 Chemokine CCL4 Chemokine CCL5 - pharmacology Chemokines, CC - antagonists & inhibitors Chemokines, CC - physiology Chemotactic Factors, Eosinophil - pharmacology Cytokines - pharmacology Disease Models, Animal Hypersensitivity - immunology Immunohistochemistry Inflammation - immunology Leukocytes - drug effects Leukocytes - metabolism Lung - cytology Lung - immunology Macrophage Inflammatory Proteins - pharmacology Mice Mice, Inbred Strains Monocyte Chemoattractant Proteins - pharmacology Ovalbumin - immunology RNA, Messenger - metabolism
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