Differences in STIM1 and TRPC expression in proximal and distal pulmonary arterial smooth muscle are associated with differences in Ca2+ responses to hypoxia

Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland Submitted 3 February 2008 ; accepted in final form 16 April 2008 Hypoxic pulmonary vasoconstriction (HPV) requires Ca 2+ influx through store-operated Ca 2+ channels (S...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2008-07, Vol.295 (1), p.L104-L113
Hauptverfasser:	Lu, Wenju, Wang, Jian, Shimoda, Larissa A, Sylvester, J. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Calcium Signaling Gene Expression Regulation Hypoxia - metabolism Hypoxia - pathology Male Membrane Glycoproteins - biosynthesis Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Organ Specificity Protein Isoforms - biosynthesis Pulmonary Artery - metabolism Pulmonary Artery - pathology Rats Rats, Wistar RNA, Messenger - biosynthesis Sarcoplasmic Reticulum - metabolism Sarcoplasmic Reticulum - pathology Stromal Interaction Molecule 1 TRPC Cation Channels - biosynthesis
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