The proverbial chicken or the egg? Dissection of the role of cell-free hemoglobin versus reactive oxygen species in sickle cell pathophysiology

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology. Heart and circulatory physiology 2008-07, Vol.295 (1), p.H4-H7
Hauptverfasser:	Krajewski, Megan L, Hsu, Lewis L, Gladwin, Mark T
Format:	Artikel
Sprache:	eng
Schlagworte:	Anemia, Sickle Cell - drug therapy Anemia, Sickle Cell - metabolism Anemia, Sickle Cell - physiopathology Animals Arginine - pharmacology Disease Models, Animal Hemodynamics - drug effects Hemoglobins - metabolism Hemolysis - drug effects Humans Microcirculation - drug effects Microcirculation - metabolism Nitric Oxide - metabolism Nitric Oxide Donors - pharmacology Nitric Oxide Synthase - metabolism Oxidative Stress - drug effects Tyrosine - analogs & derivatives Tyrosine - metabolism Vasodilator Agents - metabolism Vasodilator Agents - pharmacology
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