Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

A hallmark of mammalian embryonic development is the widespread induction of microRNA (miRNA) expression. Surprisingly, the transcription of many of these small, noncoding RNAs is unchanged through development; rather, a post-transcriptional regulatory event prevents accumulation of the mature miRNA...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	RNA (Cambridge) 2008-08, Vol.14 (8), p.1539-1549
Hauptverfasser:	Newman, Martin A, Thomson, J Michael, Hammond, Scott M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Caenorhabditis elegans Cell Line Cell-Free System HeLa Cells Humans Mice MicroRNAs - metabolism RNA Interference RNA-Binding Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!