Mefloquine, sulfadoxine, and pyrimethamine in the treatment of symptomatic falciparum malaria: a double-blind trial for determining the most effective dose

A total of 89 adult male Thai patients who had acute, uncomplicated falciparum malaria were treated in a double-blind randomized trial with a single oral dose of two or three tablets, each consisting of 250 mg mefloquine, 500 mg sulfadoxine, and 25 mg pyrimethamine (MSP). The two-tablet regimen prod...

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Veröffentlicht in:	Bulletin of the World Health Organization 1987, Vol.65 (3), p.363-367
Hauptverfasser:	HARINASUTA, T, BUNNAG, D, VANIJANOND, S, CHAROENLARP, P, SUNTHARASMAI, P, CHITAMAS, S, SHETH, U. K, WERNSDORFER, W. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Animals Antimalarials - administration & dosage Antimalarials - therapeutic use Biological and medical sciences Double-Blind Method Drug Combinations - administration & dosage Drug Combinations - therapeutic use Human protozoal diseases Humans Infectious diseases Malaria Malaria - drug therapy Male Medical sciences Mefloquine - analogs & derivatives Parasitic diseases Plasmodium falciparum Protozoal diseases Pyrimethamine - administration & dosage Pyrimethamine - therapeutic use Quinolines - administration & dosage Quinolines - therapeutic use Random Allocation Sulfadoxine - administration & dosage Sulfadoxine - therapeutic use Sulfanilamides - therapeutic use Thailand Tropical medicine
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