A phase II/III double-blind, dose-finding clinical trial of a combination of mefloquine, sulfadoxine, and pyrimethamine (Fansimef) in falciparum malaria

Fansimef is a combination of 250 mg mefloquine (base), 500 mg sulfadoxine, and 25 mg pyrimethamine per tablet. One hundred and fifty adult male Brazilian patients at Belém (Pará), who had peripheral blood smears positive for Plasmodium falciparum, with or without clinical symptoms of falciparum mala...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of the World Health Organization 1987, Vol.65 (3), p.357-361
Hauptverfasser:	DE SOUZA, J. M, SHETH, U. K, WERNSDORFER, W. H, TRIGG, P. I, DOBERSTYN, E. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adolescent Adult Animals Antimalarials - administration & dosage Antimalarials - adverse effects Antimalarials - therapeutic use Biological and medical sciences Brazil Double-Blind Method Drug Combinations - administration & dosage Drug Combinations - adverse effects Drug Combinations - therapeutic use Drug Evaluation Human protozoal diseases Humans Infectious diseases Malaria Malaria - drug therapy Male Medical sciences Mefloquine - analogs & derivatives Middle Aged Parasitic diseases Plasmodium falciparum Protozoal diseases Pyrimethamine - administration & dosage Pyrimethamine - adverse effects Pyrimethamine - therapeutic use Quinolines - administration & dosage Quinolines - adverse effects Quinolines - therapeutic use Random Allocation Sulfadoxine - administration & dosage Sulfadoxine - adverse effects Sulfadoxine - therapeutic use Sulfanilamides - therapeutic use Tropical medicine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!