Neuronal effects of 4- t-Butylcatechol: A model for catechol-containing antioxidants

Many herbal medicines and dietary supplements sold as aids to improve memory or treat neurodegenerative diseases or have other favorable effects on the CNS contain a catechol or similar 1,2-dihydroxy aromatic moiety in their structure. As an approach to isolate and examine the neuroprotective proper...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology and applied pharmacology 2008-04, Vol.228 (2), p.247-255
Hauptverfasser:	Lo, Yi-Ching, Liu, Yuxin, Lin, Yi-Chin, Shih, Yu-Tzu, Liu, Chi-Ming, Burka, Leo T.
Format:	Artikel
Sprache:	eng
Schlagworte:	4- t-Butylcatechol 60 APPLIED LIFE SCIENCES AIDS Animals Antioxidant ANTIOXIDANTS Antioxidants - pharmacology APOPTOSIS Biological and medical sciences Catechols - pharmacology Cell Line Cell Line, Tumor Cell Survival - drug effects Coculture Techniques Cyclooxygenase 2 - metabolism Cyclooxygenase Inhibitors - pharmacology Dose-Response Relationship, Drug DRUGS Heme Oxygenase-1 - metabolism Humans IN VITRO INFLAMMATION Lipopolysaccharides - pharmacology Medical sciences Membrane Glycoproteins - metabolism Membrane Potential, Mitochondrial - drug effects Microglia Microglia - cytology Microglia - drug effects Microglia - metabolism MITOCHONDRIA NADPH Oxidase 2 NADPH Oxidases - metabolism NERVE CELLS NERVOUS SYSTEM DISEASES Neurons Neurons - cytology Neurons - drug effects Neurons - metabolism Nitric Oxide Synthase Type I - antagonists & inhibitors Nitric Oxide Synthase Type I - metabolism Nitric Oxide Synthase Type II - antagonists & inhibitors Nitric Oxide Synthase Type II - metabolism Nitrobenzenes - pharmacology OXIDATION Oxidative stress Oxidative Stress - drug effects Oxidopamine - pharmacology PYROCATECHOL Reactive Oxygen Species - metabolism Sulfonamides - pharmacology TOXICITY Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!