The Influence of the Cylindrical Shape of the Nucleosomes and H1 Defects on Properties of Chromatin

We present a model improving the two-angle model for interphase chromatin (E2A model). This model takes into account the cylindrical shape of the histone octamers, the H1 histones in front of the nucleosomes, and the distance d between the in and outgoing DNA strands orthogonal to the axis of the co...

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Veröffentlicht in:	Biophysical journal 2008-06, Vol.94 (11), p.4165-4172
Hauptverfasser:	Diesinger, Philipp M., Heermann, Dieter W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Biophysical Theory and Modeling Cellular biology Chromatin Chromatin - chemistry Chromatin - ultrastructure Computer Simulation Deoxyribonucleic acid DNA Eukaryotes Histones - chemistry Histones - ultrastructure Macromolecular Substances - chemistry Models, Chemical Models, Molecular Molecular biology Molecular Conformation Nucleosomes - chemistry Nucleosomes - ultrastructure Protein Binding
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