Quantifying Reductive Carboxylation Flux of Glutamine to Lipid in a Brown Adipocyte Cell Line

We previously reported that glutamine was a major source of carbon for de novo fatty acid synthesis in a brown adipocyte cell line. The pathway for fatty acid synthesis from glutamine may follow either of two distinct pathways after it enters the citric acid cycle. The glutaminolysis pathway follows...

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Veröffentlicht in:The Journal of biological chemistry 2008-07, Vol.283 (30), p.20621-20627
Hauptverfasser: Yoo, Hyuntae, Antoniewicz, Maciek R., Stephanopoulos, Gregory, Kelleher, Joanne K.
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Sprache:eng
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