Requirement of HDAC6 for Transforming Growth Factor-β1-induced Epithelial-Mesenchymal Transition

The aberrant expression of transforming growth factor (TGF)-β1 in the tumor microenvironment and fibrotic lesions plays a critical role in tumor progression and tissue fibrosis by inducing epithelial-mesenchymal transition (EMT). EMT promotes tumor cell motility and invasiveness. How EMT affects mot...

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Veröffentlicht in:	The Journal of biological chemistry 2008-07, Vol.283 (30), p.21065-21073
Hauptverfasser:	Shan, Bin, Yao, Tso-pang, Nguyen, Hong T., Zhuo, Ying, Levy, Dawn R., Klingsberg, Ross C., Tao, Hui, Palmer, Michael L., Holder, Kevin N., Lasky, Joseph A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Mechanisms of Signal Transduction
Online-Zugang:	Volltext
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