Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise
Objective: To investigate indices of left ventricular (LV) function before and after a 224 km Ironman triathlon, specifically in the presence of unaltered haemodynamic loading. Method: LV loading and function were assessed before and after the race using M mode and Doppler echocardiography in 39 (me...
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| Veröffentlicht in: | British journal of sports medicine 2006-06, Vol.40 (6), p.536-540 |
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| description | Objective: To investigate indices of left ventricular (LV) function before and after a 224 km Ironman triathlon, specifically in the presence of unaltered haemodynamic loading. Method: LV loading and function were assessed before and after the race using M mode and Doppler echocardiography in 39 (mean (SD) age 33 (8) years, body mass 77.6 (8.6) kg; 36 male) triathletes in the Trendelenburg position. Specifically left ventricular end diastolic volume (LVEDV) was assessed to estimate preload, and systolic blood pressure to estimate afterload as well as heart rate (HR). Systolic functional indices included ejection fraction (EF) and the end systolic pressure/volume ratio (ESPV), and diastolic functional indices included peak mitral flow velocity in early (E) and atrial (A) filling as well as the ratio E/A. Data obtained before and after the race were compared by t tests, and delta LV functional indices were correlated with delta heart rate. Results: Preload (LVEDV: 143 (34) ml before v 147 (34) ml after) and afterload (systolic blood pressure 121 (13) v 115 (20) mm Hg) were not significantly altered after the race (p>0.05), nor were EF (61 (8)% v 58 (10)%) and ESPV (2.4 (0.9) v 2.1 (0.8) mm Hg/cm3). The diastolic filling ratio E/A was significantly reduced after the race (1.73 (0.25) v 1.54 (0.23); p |
| doi_str_mv | 10.1136/bjsm.2005.024745 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2465110</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>17234332</sourcerecordid><originalsourceid>FETCH-LOGICAL-b554t-937af7d04d0605a124440d9d70ea6f7955dc284750e3eb09b85ca5ff4f99dc143</originalsourceid><addsrcrecordid>eNqNkk1v1DAQhiMEoqVw54QskLhAlnE8jpMLElrRgqgKh8LVcpxJ8ZI4i-1U3R_C_yXbXcqHhOA00szzzpfeLHvIYcG5KF80qzgsCgC5gAIVylvZIUclcsAKbmeHIKDMRanwILsX4wqAFxKqu9kBLyUqjniYffsQqB9NywbjfCJvvCW2DmMimyIzF3M2JmZYS-tAMbrRM-dZT11il-RTcHbqTWBxE9PYO_ucNVNifkysdeZHqpu8TdfKYaA5n6jfMNMlCmzqUzDk2ylcD6YrCtZFup_d6Uwf6cE-HmUfj1-fL9_kp-9P3i5fneaNlJjyWijTqRawhRKk4QUiQlu3CsiUnaqlbG1RoZJAghqom0paI7sOu7puLUdxlL3c9V1Pzbya3V5ker0ObjBho0fj9O8V7z7ri_FSF1hKzmFu8HTfIIxfJ4pJDy5a6nvjaZyiLisAEP8BclUIFKKYwcd_gKtxCn7-guY1YlmpYrv3k79CStUAlar4TMGOsmGMMVB3cxgHvfWP3vpHb_2jd_6ZJY9-fchPwd4wM5DvABcTXd3UTfiiSyWU1Geflro-O0Y8Uef63cw_2_HNsPr3-O_VSOGB</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1779008781</pqid></control><display><type>article</type><title>Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise</title><source>MEDLINE</source><source>BMJ Journals - NESLi2</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><creator>Hassan, M Y ; Noakes, T D ; Berlyn, P ; Shave, R ; George, K</creator><creatorcontrib>Hassan, M Y ; Noakes, T D ; Berlyn, P ; Shave, R ; George, K</creatorcontrib><description>Objective: To investigate indices of left ventricular (LV) function before and after a 224 km Ironman triathlon, specifically in the presence of unaltered haemodynamic loading. Method: LV loading and function were assessed before and after the race using M mode and Doppler echocardiography in 39 (mean (SD) age 33 (8) years, body mass 77.6 (8.6) kg; 36 male) triathletes in the Trendelenburg position. Specifically left ventricular end diastolic volume (LVEDV) was assessed to estimate preload, and systolic blood pressure to estimate afterload as well as heart rate (HR). Systolic functional indices included ejection fraction (EF) and the end systolic pressure/volume ratio (ESPV), and diastolic functional indices included peak mitral flow velocity in early (E) and atrial (A) filling as well as the ratio E/A. Data obtained before and after the race were compared by t tests, and delta LV functional indices were correlated with delta heart rate. Results: Preload (LVEDV: 143 (34) ml before v 147 (34) ml after) and afterload (systolic blood pressure 121 (13) v 115 (20) mm Hg) were not significantly altered after the race (p>0.05), nor were EF (61 (8)% v 58 (10)%) and ESPV (2.4 (0.9) v 2.1 (0.8) mm Hg/cm3). The diastolic filling ratio E/A was significantly reduced after the race (1.73 (0.25) v 1.54 (0.23); p<0.05) due primarily to a reduction in E. HR was significantly higher after the race (57 (9) v 75 (8) beats/min; p<0.05), but delta HR was not related to delta E/A (p>0.05). Conclusion: When preload and afterload are unaltered after the race, because of the adoption of a unique assessment posture, LV systolic function is not depressed. A depression in LV diastolic function persists which is not explained by an increase in heart rate after the race.</description><identifier>ISSN: 0306-3674</identifier><identifier>EISSN: 1473-0480</identifier><identifier>DOI: 10.1136/bjsm.2005.024745</identifier><identifier>PMID: 16547144</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine</publisher><subject>Adult ; Athletes ; Bicycling - physiology ; Blood Flow Velocity - physiology ; Blood pressure ; Blood Pressure - physiology ; cardiac fatigue ; Cardiovascular system ; Diastole - physiology ; E/A ; Echocardiography, Doppler ; ejection fraction ; end systolic pressure/volume ratio ; ESPV ; Fatigue ; Female ; Heart rate ; Heart Rate - physiology ; Humans ; Laboratories ; Male ; Muscle Fatigue - physiology ; Original ; Physical Endurance - physiology ; Posture ; prolonged exercise ; ratio of early to late peak diastolic filling ; Running ; Running - physiology ; Sports medicine ; stroke volume ; Studies ; Swimming - physiology ; Systole - physiology ; Trendelenburg position ; Triathlon ; Ultrasonic imaging ; Ventricular Function, Left - physiology</subject><ispartof>British journal of sports medicine, 2006-06, Vol.40 (6), p.536-540</ispartof><rights>Copyright 2006 British Journal of Sports Medicine</rights><rights>Copyright: 2006 Copyright 2006 British Journal of Sports Medicine</rights><rights>Copyright BMJ Publishing Group Jun 2006</rights><rights>Copyright ©2006 British Journal of Sports Medicine.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b554t-937af7d04d0605a124440d9d70ea6f7955dc284750e3eb09b85ca5ff4f99dc143</citedby><cites>FETCH-LOGICAL-b554t-937af7d04d0605a124440d9d70ea6f7955dc284750e3eb09b85ca5ff4f99dc143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://bjsm.bmj.com/content/40/6/536.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://bjsm.bmj.com/content/40/6/536.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,230,314,723,776,780,881,3183,23550,27901,27902,53766,53768,77343,77374</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16547144$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hassan, M Y</creatorcontrib><creatorcontrib>Noakes, T D</creatorcontrib><creatorcontrib>Berlyn, P</creatorcontrib><creatorcontrib>Shave, R</creatorcontrib><creatorcontrib>George, K</creatorcontrib><title>Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise</title><title>British journal of sports medicine</title><addtitle>Br J Sports Med</addtitle><description>Objective: To investigate indices of left ventricular (LV) function before and after a 224 km Ironman triathlon, specifically in the presence of unaltered haemodynamic loading. Method: LV loading and function were assessed before and after the race using M mode and Doppler echocardiography in 39 (mean (SD) age 33 (8) years, body mass 77.6 (8.6) kg; 36 male) triathletes in the Trendelenburg position. Specifically left ventricular end diastolic volume (LVEDV) was assessed to estimate preload, and systolic blood pressure to estimate afterload as well as heart rate (HR). Systolic functional indices included ejection fraction (EF) and the end systolic pressure/volume ratio (ESPV), and diastolic functional indices included peak mitral flow velocity in early (E) and atrial (A) filling as well as the ratio E/A. Data obtained before and after the race were compared by t tests, and delta LV functional indices were correlated with delta heart rate. Results: Preload (LVEDV: 143 (34) ml before v 147 (34) ml after) and afterload (systolic blood pressure 121 (13) v 115 (20) mm Hg) were not significantly altered after the race (p>0.05), nor were EF (61 (8)% v 58 (10)%) and ESPV (2.4 (0.9) v 2.1 (0.8) mm Hg/cm3). The diastolic filling ratio E/A was significantly reduced after the race (1.73 (0.25) v 1.54 (0.23); p<0.05) due primarily to a reduction in E. HR was significantly higher after the race (57 (9) v 75 (8) beats/min; p<0.05), but delta HR was not related to delta E/A (p>0.05). Conclusion: When preload and afterload are unaltered after the race, because of the adoption of a unique assessment posture, LV systolic function is not depressed. A depression in LV diastolic function persists which is not explained by an increase in heart rate after the race.</description><subject>Adult</subject><subject>Athletes</subject><subject>Bicycling - physiology</subject><subject>Blood Flow Velocity - physiology</subject><subject>Blood pressure</subject><subject>Blood Pressure - physiology</subject><subject>cardiac fatigue</subject><subject>Cardiovascular system</subject><subject>Diastole - physiology</subject><subject>E/A</subject><subject>Echocardiography, Doppler</subject><subject>ejection fraction</subject><subject>end systolic pressure/volume ratio</subject><subject>ESPV</subject><subject>Fatigue</subject><subject>Female</subject><subject>Heart rate</subject><subject>Heart Rate - physiology</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Male</subject><subject>Muscle Fatigue - physiology</subject><subject>Original</subject><subject>Physical Endurance - physiology</subject><subject>Posture</subject><subject>prolonged exercise</subject><subject>ratio of early to late peak diastolic filling</subject><subject>Running</subject><subject>Running - physiology</subject><subject>Sports medicine</subject><subject>stroke volume</subject><subject>Studies</subject><subject>Swimming - physiology</subject><subject>Systole - physiology</subject><subject>Trendelenburg position</subject><subject>Triathlon</subject><subject>Ultrasonic imaging</subject><subject>Ventricular Function, Left - physiology</subject><issn>0306-3674</issn><issn>1473-0480</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkk1v1DAQhiMEoqVw54QskLhAlnE8jpMLElrRgqgKh8LVcpxJ8ZI4i-1U3R_C_yXbXcqHhOA00szzzpfeLHvIYcG5KF80qzgsCgC5gAIVylvZIUclcsAKbmeHIKDMRanwILsX4wqAFxKqu9kBLyUqjniYffsQqB9NywbjfCJvvCW2DmMimyIzF3M2JmZYS-tAMbrRM-dZT11il-RTcHbqTWBxE9PYO_ucNVNifkysdeZHqpu8TdfKYaA5n6jfMNMlCmzqUzDk2ylcD6YrCtZFup_d6Uwf6cE-HmUfj1-fL9_kp-9P3i5fneaNlJjyWijTqRawhRKk4QUiQlu3CsiUnaqlbG1RoZJAghqom0paI7sOu7puLUdxlL3c9V1Pzbya3V5ker0ObjBho0fj9O8V7z7ri_FSF1hKzmFu8HTfIIxfJ4pJDy5a6nvjaZyiLisAEP8BclUIFKKYwcd_gKtxCn7-guY1YlmpYrv3k79CStUAlar4TMGOsmGMMVB3cxgHvfWP3vpHb_2jd_6ZJY9-fchPwd4wM5DvABcTXd3UTfiiSyWU1Geflro-O0Y8Uef63cw_2_HNsPr3-O_VSOGB</recordid><startdate>20060601</startdate><enddate>20060601</enddate><creator>Hassan, M Y</creator><creator>Noakes, T D</creator><creator>Berlyn, P</creator><creator>Shave, R</creator><creator>George, K</creator><general>BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><general>BMJ Group</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M2P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20060601</creationdate><title>Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise</title><author>Hassan, M Y ; Noakes, T D ; Berlyn, P ; Shave, R ; George, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b554t-937af7d04d0605a124440d9d70ea6f7955dc284750e3eb09b85ca5ff4f99dc143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Athletes</topic><topic>Bicycling - physiology</topic><topic>Blood Flow Velocity - physiology</topic><topic>Blood pressure</topic><topic>Blood Pressure - physiology</topic><topic>cardiac fatigue</topic><topic>Cardiovascular system</topic><topic>Diastole - physiology</topic><topic>E/A</topic><topic>Echocardiography, Doppler</topic><topic>ejection fraction</topic><topic>end systolic pressure/volume ratio</topic><topic>ESPV</topic><topic>Fatigue</topic><topic>Female</topic><topic>Heart rate</topic><topic>Heart Rate - physiology</topic><topic>Humans</topic><topic>Laboratories</topic><topic>Male</topic><topic>Muscle Fatigue - physiology</topic><topic>Original</topic><topic>Physical Endurance - physiology</topic><topic>Posture</topic><topic>prolonged exercise</topic><topic>ratio of early to late peak diastolic filling</topic><topic>Running</topic><topic>Running - physiology</topic><topic>Sports medicine</topic><topic>stroke volume</topic><topic>Studies</topic><topic>Swimming - physiology</topic><topic>Systole - physiology</topic><topic>Trendelenburg position</topic><topic>Triathlon</topic><topic>Ultrasonic imaging</topic><topic>Ventricular Function, Left - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hassan, M Y</creatorcontrib><creatorcontrib>Noakes, T D</creatorcontrib><creatorcontrib>Berlyn, P</creatorcontrib><creatorcontrib>Shave, R</creatorcontrib><creatorcontrib>George, K</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>British journal of sports medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hassan, M Y</au><au>Noakes, T D</au><au>Berlyn, P</au><au>Shave, R</au><au>George, K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise</atitle><jtitle>British journal of sports medicine</jtitle><addtitle>Br J Sports Med</addtitle><date>2006-06-01</date><risdate>2006</risdate><volume>40</volume><issue>6</issue><spage>536</spage><epage>540</epage><pages>536-540</pages><issn>0306-3674</issn><eissn>1473-0480</eissn><abstract>Objective: To investigate indices of left ventricular (LV) function before and after a 224 km Ironman triathlon, specifically in the presence of unaltered haemodynamic loading. Method: LV loading and function were assessed before and after the race using M mode and Doppler echocardiography in 39 (mean (SD) age 33 (8) years, body mass 77.6 (8.6) kg; 36 male) triathletes in the Trendelenburg position. Specifically left ventricular end diastolic volume (LVEDV) was assessed to estimate preload, and systolic blood pressure to estimate afterload as well as heart rate (HR). Systolic functional indices included ejection fraction (EF) and the end systolic pressure/volume ratio (ESPV), and diastolic functional indices included peak mitral flow velocity in early (E) and atrial (A) filling as well as the ratio E/A. Data obtained before and after the race were compared by t tests, and delta LV functional indices were correlated with delta heart rate. Results: Preload (LVEDV: 143 (34) ml before v 147 (34) ml after) and afterload (systolic blood pressure 121 (13) v 115 (20) mm Hg) were not significantly altered after the race (p>0.05), nor were EF (61 (8)% v 58 (10)%) and ESPV (2.4 (0.9) v 2.1 (0.8) mm Hg/cm3). The diastolic filling ratio E/A was significantly reduced after the race (1.73 (0.25) v 1.54 (0.23); p<0.05) due primarily to a reduction in E. HR was significantly higher after the race (57 (9) v 75 (8) beats/min; p<0.05), but delta HR was not related to delta E/A (p>0.05). Conclusion: When preload and afterload are unaltered after the race, because of the adoption of a unique assessment posture, LV systolic function is not depressed. A depression in LV diastolic function persists which is not explained by an increase in heart rate after the race.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Association of Sport and Exercise Medicine</pub><pmid>16547144</pmid><doi>10.1136/bjsm.2005.024745</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Athletes Bicycling - physiology Blood Flow Velocity - physiology Blood pressure Blood Pressure - physiology cardiac fatigue Cardiovascular system Diastole - physiology E/A Echocardiography, Doppler ejection fraction end systolic pressure/volume ratio ESPV Fatigue Female Heart rate Heart Rate - physiology Humans Laboratories Male Muscle Fatigue - physiology Original Physical Endurance - physiology Posture prolonged exercise ratio of early to late peak diastolic filling Running Running - physiology Sports medicine stroke volume Studies Swimming - physiology Systole - physiology Trendelenburg position Triathlon Ultrasonic imaging Ventricular Function, Left - physiology |
| title | Preload maintenance protects against a depression in left ventricular systolic, but not diastolic, function immediately after ultraendurance exercise |
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