Hypersensitivity reaction with intravenous GnRH after pulsatile subcutaneous GnRH treatment in male hypogonadotrophic hypogonadism

Chronic pulsatile subcutaneous administration of low doses of gonadotrophin releasing hormone (GnRH) is an effective therapy for men with hypogonadotrophic hypogonadism. Hypersensitivity reactions to GnRH are rare. We wish to report hypersensitivity reactions with intravenous GnRH after low dose sub...

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Veröffentlicht in:	Postgraduate medical journal 1988-03, Vol.64 (749), p.245-246
Hauptverfasser:	Popovic, V, Milosevic, Z, Djukanovic, R, Micic, D, Nesovic, M, Manojlovic, D, Djordjevic, P, Micic, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Bronchial Spasm - chemically induced Drug Administration Schedule Drug Hypersensitivity - etiology Erythema - chemically induced Humans Hypogonadism - drug therapy Injections, Intravenous Injections, Subcutaneous Male Pituitary Hormone-Releasing Hormones - administration & dosage Pituitary Hormone-Releasing Hormones - adverse effects
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Zusammenfassung:	Chronic pulsatile subcutaneous administration of low doses of gonadotrophin releasing hormone (GnRH) is an effective therapy for men with hypogonadotrophic hypogonadism. Hypersensitivity reactions to GnRH are rare. We wish to report hypersensitivity reactions with intravenous GnRH after low dose subcutaneous pulsatile GnRH treatment in two men with hypogonadotrophic hypogonadism due to suprasellar disease.
ISSN:	0032-5473 1469-0756
DOI:	10.1136/pgmj.64.749.245