The evaluation of cefuroxime in the prevention of postoperative infection
Patients undergoing biliary surgery received either 750 mg cefuroxime i.m. with the premedication and then 8 hourly for 3 days ((group A) or 1.5 g cefuroxime i.v. at the time of induction of anaesthesia (group B) or not treatment (group C). Wound infections occurred in 3 out of 35 patients in group...
Gespeichert in:
| Veröffentlicht in: | Postgraduate medical journal 1981-06, Vol.57 (668), p.363-365 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 365 |
|---|---|
| container_issue | 668 |
| container_start_page | 363 |
| container_title | Postgraduate medical journal |
| container_volume | 57 |
| creator | Croton, R. S. Sykes, D. Treanor, J. Wake, P. Green, H. T. Knowles, M. A. Eilon, L. A. |
| description | Patients undergoing biliary surgery received either 750 mg cefuroxime i.m. with the premedication and then 8 hourly for 3 days ((group A) or 1.5 g cefuroxime i.v. at the time of induction of anaesthesia (group B) or not treatment (group C). Wound infections occurred in 3 out of 35 patients in group A, 1 out of 40 patients in group B and 11 out of 39 patients in group C (group B significantly different than group C, P less than 0.05). Eight patients (23%) in group C had chest complications. Cefuroxime was effective in the reduction of wound sepsis following biliary surgery and 1.5 g i.v. administered during induction of anaesthesia is the dosage of choice. The incidence of chest infection tended to be lower in patients receiving cefuroxime but many more patients would have to be studied for a conclusive result. |
| doi_str_mv | 10.1136/pgmj.57.668.363 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2424908</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3972293631</sourcerecordid><originalsourceid>FETCH-LOGICAL-b489t-5e2cefe801e0233d50d3885b5cbab75418742d590e5f44738b311267f14e4f013</originalsourceid><addsrcrecordid>eNqFkcuL1EAQhxtR1nH17EkICB6EzHaln7kIMqi7MPiA0WvTyVR2Mybp2J0M639vDTMO6sVTHb6vXvwYew58CSD01Xjb75bKLLW2S6HFA7YAqcucG6UfsgXnosiVNOIxe5LSjnMQRsIFu9CmVBrkgt1s7jDDve9mP7VhyEKT1djMMdy3PWbtkE3Ex4h7HH7zMaQpjBipYX9QGqwP6Cl71Pgu4bNTvWRf37_brK7z9acPN6u367yStpxyhQUtQMsBeSHEVvGtsFZVqq58ZZQEa2SxVSVH1Ui63FYCoNCmAYmyoQcu2Zvj3HGuetzWdFj0nRtj2_v40wXfur_J0N6527B3hSxkyS0NeHUaEMOPGdPk-jbV2HV-wDAnZ4QRGkxJ4st_xF2Y40DPOTCGW5CGK7KujlYdQ0oRm_MpwN0hI3fIyCnjKCNHGVHHiz8_OPunUIjnR96mCe_P2MfvpAij3MdvK_dlba83JXx2nPzXR7-iPf9b_gskA6qt</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1770814705</pqid></control><display><type>article</type><title>The evaluation of cefuroxime in the prevention of postoperative infection</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Croton, R. S. ; Sykes, D. ; Treanor, J. ; Wake, P. ; Green, H. T. ; Knowles, M. A. ; Eilon, L. A.</creator><creatorcontrib>Croton, R. S. ; Sykes, D. ; Treanor, J. ; Wake, P. ; Green, H. T. ; Knowles, M. A. ; Eilon, L. A.</creatorcontrib><description>Patients undergoing biliary surgery received either 750 mg cefuroxime i.m. with the premedication and then 8 hourly for 3 days ((group A) or 1.5 g cefuroxime i.v. at the time of induction of anaesthesia (group B) or not treatment (group C). Wound infections occurred in 3 out of 35 patients in group A, 1 out of 40 patients in group B and 11 out of 39 patients in group C (group B significantly different than group C, P less than 0.05). Eight patients (23%) in group C had chest complications. Cefuroxime was effective in the reduction of wound sepsis following biliary surgery and 1.5 g i.v. administered during induction of anaesthesia is the dosage of choice. The incidence of chest infection tended to be lower in patients receiving cefuroxime but many more patients would have to be studied for a conclusive result.</description><identifier>ISSN: 0032-5473</identifier><identifier>EISSN: 1469-0756</identifier><identifier>DOI: 10.1136/pgmj.57.668.363</identifier><identifier>PMID: 6795614</identifier><language>eng</language><publisher>England: The Fellowship of Postgraduate Medicine</publisher><subject>Adult ; Aged ; Bacterial Infections - prevention & control ; Biliary Tract Surgical Procedures ; Cefuroxime - administration & dosage ; Cefuroxime - therapeutic use ; Cephalosporins - therapeutic use ; Drug Administration Schedule ; Drug Evaluation ; Female ; Humans ; Male ; Middle Aged ; Postoperative Complications - prevention & control ; Premedication ; Respiratory Tract Infections - prevention & control ; Surgical Wound Infection - prevention & control</subject><ispartof>Postgraduate medical journal, 1981-06, Vol.57 (668), p.363-365</ispartof><rights>Copyright BMJ Publishing Group LTD Jun 1981</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b489t-5e2cefe801e0233d50d3885b5cbab75418742d590e5f44738b311267f14e4f013</citedby><cites>FETCH-LOGICAL-b489t-5e2cefe801e0233d50d3885b5cbab75418742d590e5f44738b311267f14e4f013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424908/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2424908/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6795614$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Croton, R. S.</creatorcontrib><creatorcontrib>Sykes, D.</creatorcontrib><creatorcontrib>Treanor, J.</creatorcontrib><creatorcontrib>Wake, P.</creatorcontrib><creatorcontrib>Green, H. T.</creatorcontrib><creatorcontrib>Knowles, M. A.</creatorcontrib><creatorcontrib>Eilon, L. A.</creatorcontrib><title>The evaluation of cefuroxime in the prevention of postoperative infection</title><title>Postgraduate medical journal</title><addtitle>Postgrad Med J</addtitle><description>Patients undergoing biliary surgery received either 750 mg cefuroxime i.m. with the premedication and then 8 hourly for 3 days ((group A) or 1.5 g cefuroxime i.v. at the time of induction of anaesthesia (group B) or not treatment (group C). Wound infections occurred in 3 out of 35 patients in group A, 1 out of 40 patients in group B and 11 out of 39 patients in group C (group B significantly different than group C, P less than 0.05). Eight patients (23%) in group C had chest complications. Cefuroxime was effective in the reduction of wound sepsis following biliary surgery and 1.5 g i.v. administered during induction of anaesthesia is the dosage of choice. The incidence of chest infection tended to be lower in patients receiving cefuroxime but many more patients would have to be studied for a conclusive result.</description><subject>Adult</subject><subject>Aged</subject><subject>Bacterial Infections - prevention & control</subject><subject>Biliary Tract Surgical Procedures</subject><subject>Cefuroxime - administration & dosage</subject><subject>Cefuroxime - therapeutic use</subject><subject>Cephalosporins - therapeutic use</subject><subject>Drug Administration Schedule</subject><subject>Drug Evaluation</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Postoperative Complications - prevention & control</subject><subject>Premedication</subject><subject>Respiratory Tract Infections - prevention & control</subject><subject>Surgical Wound Infection - prevention & control</subject><issn>0032-5473</issn><issn>1469-0756</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkcuL1EAQhxtR1nH17EkICB6EzHaln7kIMqi7MPiA0WvTyVR2Mybp2J0M639vDTMO6sVTHb6vXvwYew58CSD01Xjb75bKLLW2S6HFA7YAqcucG6UfsgXnosiVNOIxe5LSjnMQRsIFu9CmVBrkgt1s7jDDve9mP7VhyEKT1djMMdy3PWbtkE3Ex4h7HH7zMaQpjBipYX9QGqwP6Cl71Pgu4bNTvWRf37_brK7z9acPN6u367yStpxyhQUtQMsBeSHEVvGtsFZVqq58ZZQEa2SxVSVH1Ui63FYCoNCmAYmyoQcu2Zvj3HGuetzWdFj0nRtj2_v40wXfur_J0N6527B3hSxkyS0NeHUaEMOPGdPk-jbV2HV-wDAnZ4QRGkxJ4st_xF2Y40DPOTCGW5CGK7KujlYdQ0oRm_MpwN0hI3fIyCnjKCNHGVHHiz8_OPunUIjnR96mCe_P2MfvpAij3MdvK_dlba83JXx2nPzXR7-iPf9b_gskA6qt</recordid><startdate>19810601</startdate><enddate>19810601</enddate><creator>Croton, R. S.</creator><creator>Sykes, D.</creator><creator>Treanor, J.</creator><creator>Wake, P.</creator><creator>Green, H. T.</creator><creator>Knowles, M. A.</creator><creator>Eilon, L. A.</creator><general>The Fellowship of Postgraduate Medicine</general><general>Oxford University Press</general><general>BMJ Group</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19810601</creationdate><title>The evaluation of cefuroxime in the prevention of postoperative infection</title><author>Croton, R. S. ; Sykes, D. ; Treanor, J. ; Wake, P. ; Green, H. T. ; Knowles, M. A. ; Eilon, L. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b489t-5e2cefe801e0233d50d3885b5cbab75418742d590e5f44738b311267f14e4f013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Bacterial Infections - prevention & control</topic><topic>Biliary Tract Surgical Procedures</topic><topic>Cefuroxime - administration & dosage</topic><topic>Cefuroxime - therapeutic use</topic><topic>Cephalosporins - therapeutic use</topic><topic>Drug Administration Schedule</topic><topic>Drug Evaluation</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Postoperative Complications - prevention & control</topic><topic>Premedication</topic><topic>Respiratory Tract Infections - prevention & control</topic><topic>Surgical Wound Infection - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Croton, R. S.</creatorcontrib><creatorcontrib>Sykes, D.</creatorcontrib><creatorcontrib>Treanor, J.</creatorcontrib><creatorcontrib>Wake, P.</creatorcontrib><creatorcontrib>Green, H. T.</creatorcontrib><creatorcontrib>Knowles, M. A.</creatorcontrib><creatorcontrib>Eilon, L. A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Postgraduate medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Croton, R. S.</au><au>Sykes, D.</au><au>Treanor, J.</au><au>Wake, P.</au><au>Green, H. T.</au><au>Knowles, M. A.</au><au>Eilon, L. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The evaluation of cefuroxime in the prevention of postoperative infection</atitle><jtitle>Postgraduate medical journal</jtitle><addtitle>Postgrad Med J</addtitle><date>1981-06-01</date><risdate>1981</risdate><volume>57</volume><issue>668</issue><spage>363</spage><epage>365</epage><pages>363-365</pages><issn>0032-5473</issn><eissn>1469-0756</eissn><abstract>Patients undergoing biliary surgery received either 750 mg cefuroxime i.m. with the premedication and then 8 hourly for 3 days ((group A) or 1.5 g cefuroxime i.v. at the time of induction of anaesthesia (group B) or not treatment (group C). Wound infections occurred in 3 out of 35 patients in group A, 1 out of 40 patients in group B and 11 out of 39 patients in group C (group B significantly different than group C, P less than 0.05). Eight patients (23%) in group C had chest complications. Cefuroxime was effective in the reduction of wound sepsis following biliary surgery and 1.5 g i.v. administered during induction of anaesthesia is the dosage of choice. The incidence of chest infection tended to be lower in patients receiving cefuroxime but many more patients would have to be studied for a conclusive result.</abstract><cop>England</cop><pub>The Fellowship of Postgraduate Medicine</pub><pmid>6795614</pmid><doi>10.1136/pgmj.57.668.363</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0032-5473 |
| ispartof | Postgraduate medical journal, 1981-06, Vol.57 (668), p.363-365 |
| issn | 0032-5473 1469-0756 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2424908 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Adult Aged Bacterial Infections - prevention & control Biliary Tract Surgical Procedures Cefuroxime - administration & dosage Cefuroxime - therapeutic use Cephalosporins - therapeutic use Drug Administration Schedule Drug Evaluation Female Humans Male Middle Aged Postoperative Complications - prevention & control Premedication Respiratory Tract Infections - prevention & control Surgical Wound Infection - prevention & control |
| title | The evaluation of cefuroxime in the prevention of postoperative infection |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T18%3A34%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20evaluation%20of%20cefuroxime%20in%20the%20prevention%20of%20postoperative%20infection&rft.jtitle=Postgraduate%20medical%20journal&rft.au=Croton,%20R.%20S.&rft.date=1981-06-01&rft.volume=57&rft.issue=668&rft.spage=363&rft.epage=365&rft.pages=363-365&rft.issn=0032-5473&rft.eissn=1469-0756&rft_id=info:doi/10.1136/pgmj.57.668.363&rft_dat=%3Cproquest_pubme%3E3972293631%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1770814705&rft_id=info:pmid/6795614&rfr_iscdi=true |