Plasma cholesterol concentration and extra lipid band in monoclonal gammopathies
Plasma lipids and lipoproteins were studied in 21 patients with benign monoclonal gammopathy, 21 patients with multiple myeloma and seven patients with Waldenström's macroglobulinaemia. Results were compared with those of a control group, age and sex matched. Low plasma cholesterol levels in al...
Gespeichert in:
| Veröffentlicht in: | Postgraduate medical journal 1984-07, Vol.60 (705), p.449-453 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 453 |
|---|---|
| container_issue | 705 |
| container_start_page | 449 |
| container_title | Postgraduate medical journal |
| container_volume | 60 |
| creator | Levy, Y. Aviram, M. Spira, G. Tatarsky, I. Brook, G. J. Carter, A. |
| description | Plasma lipids and lipoproteins were studied in 21 patients with benign monoclonal gammopathy, 21 patients with multiple myeloma and seven patients with Waldenström's macroglobulinaemia. Results were compared with those of a control group, age and sex matched. Low plasma cholesterol levels in all three patient groups were associated with low HDL-cholesterol concentrations. Apo A-I, but not apo B, was significantly reduced. Sixty per cent of the patients exhibited an extra lipid band on plasma lipoprotein electrophoresis, which could be an immunoglobulin-lipid complex. In these patients plasma and LDL-cholesterol levels were significantly lower than in those patients in whom this band was absent. No correlation was found between the severity of the disease and plasma lipid pattern. |
| doi_str_mv | 10.1136/pgmj.60.705.449 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2417931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>81186179</sourcerecordid><originalsourceid>FETCH-LOGICAL-b489t-44a9d772683797b352ffd2fe35074b7ffb7f4611c194a302c9002df4bb85a2a53</originalsourceid><addsrcrecordid>eNqFkcGL1DAUxoO4rGP17EkoCB6EziZNmtdchGVwXdlBV9A9eAlpm85kTJOadGT9783QYXC97CGE5Pvy3vvyQ-gVwUtCKL8YN8NuyfEScLVkTDxBC8K4KDBU_ClaYEzLomJAn6HnMe4wJhQYOUfnnFFChVig21ur4qDyduutjpMO3uatd612U1CT8S5Xrsv1fTrl1oymy5vDhXH54J1vrXfK5hs1DH5U09bo-AKd9cpG_fK4Z-j71Ydvq-ti_eXjp9XlumhYLaaCMSU6gJLXFAQ0tCr7vit7TSsMrIG-T4txQloimKK4bAXGZdezpqkrVaqKZuj9XHfcN4Pu5oGtHIMZVPgjvTLyoeLMVm78b1kyAiKlz9DbY4Hgf-1TdjmY2GprldN-H2VNSM0P1gy9-c-48_uQckdJAHBNakg_nKGL2dUGH2PQ_WkUguUBlTygkhzLhEomVOnF638TnPxHNkkvZt0kLvcnWYWfkgOFSn6-W8n13Y_rK4Cv8ib5383-JvV5rPlfDOitzA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1770818747</pqid></control><display><type>article</type><title>Plasma cholesterol concentration and extra lipid band in monoclonal gammopathies</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Levy, Y. ; Aviram, M. ; Spira, G. ; Tatarsky, I. ; Brook, G. J. ; Carter, A.</creator><creatorcontrib>Levy, Y. ; Aviram, M. ; Spira, G. ; Tatarsky, I. ; Brook, G. J. ; Carter, A.</creatorcontrib><description>Plasma lipids and lipoproteins were studied in 21 patients with benign monoclonal gammopathy, 21 patients with multiple myeloma and seven patients with Waldenström's macroglobulinaemia. Results were compared with those of a control group, age and sex matched. Low plasma cholesterol levels in all three patient groups were associated with low HDL-cholesterol concentrations. Apo A-I, but not apo B, was significantly reduced. Sixty per cent of the patients exhibited an extra lipid band on plasma lipoprotein electrophoresis, which could be an immunoglobulin-lipid complex. In these patients plasma and LDL-cholesterol levels were significantly lower than in those patients in whom this band was absent. No correlation was found between the severity of the disease and plasma lipid pattern.</description><identifier>ISSN: 0032-5473</identifier><identifier>EISSN: 1469-0756</identifier><identifier>DOI: 10.1136/pgmj.60.705.449</identifier><identifier>PMID: 6431399</identifier><language>eng</language><publisher>England: The Fellowship of Postgraduate Medicine</publisher><subject>Aged ; Apolipoproteins - blood ; Apolipoproteins A ; Apolipoproteins B ; Blood Proteins - analysis ; Cholesterol - blood ; Cholesterol, HDL ; Female ; Humans ; Hypergammaglobulinemia - blood ; Immunoglobulins ; Lipids - blood ; Lipoproteins, HDL - blood ; Male ; Middle Aged ; Multiple Myeloma - blood ; Triglycerides - blood ; Waldenstrom Macroglobulinemia - blood</subject><ispartof>Postgraduate medical journal, 1984-07, Vol.60 (705), p.449-453</ispartof><rights>Copyright BMJ Publishing Group LTD Jul 1984</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b489t-44a9d772683797b352ffd2fe35074b7ffb7f4611c194a302c9002df4bb85a2a53</citedby><cites>FETCH-LOGICAL-b489t-44a9d772683797b352ffd2fe35074b7ffb7f4611c194a302c9002df4bb85a2a53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2417931/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2417931/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27922,27923,53789,53791</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6431399$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Levy, Y.</creatorcontrib><creatorcontrib>Aviram, M.</creatorcontrib><creatorcontrib>Spira, G.</creatorcontrib><creatorcontrib>Tatarsky, I.</creatorcontrib><creatorcontrib>Brook, G. J.</creatorcontrib><creatorcontrib>Carter, A.</creatorcontrib><title>Plasma cholesterol concentration and extra lipid band in monoclonal gammopathies</title><title>Postgraduate medical journal</title><addtitle>Postgrad Med J</addtitle><description>Plasma lipids and lipoproteins were studied in 21 patients with benign monoclonal gammopathy, 21 patients with multiple myeloma and seven patients with Waldenström's macroglobulinaemia. Results were compared with those of a control group, age and sex matched. Low plasma cholesterol levels in all three patient groups were associated with low HDL-cholesterol concentrations. Apo A-I, but not apo B, was significantly reduced. Sixty per cent of the patients exhibited an extra lipid band on plasma lipoprotein electrophoresis, which could be an immunoglobulin-lipid complex. In these patients plasma and LDL-cholesterol levels were significantly lower than in those patients in whom this band was absent. No correlation was found between the severity of the disease and plasma lipid pattern.</description><subject>Aged</subject><subject>Apolipoproteins - blood</subject><subject>Apolipoproteins A</subject><subject>Apolipoproteins B</subject><subject>Blood Proteins - analysis</subject><subject>Cholesterol - blood</subject><subject>Cholesterol, HDL</subject><subject>Female</subject><subject>Humans</subject><subject>Hypergammaglobulinemia - blood</subject><subject>Immunoglobulins</subject><subject>Lipids - blood</subject><subject>Lipoproteins, HDL - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multiple Myeloma - blood</subject><subject>Triglycerides - blood</subject><subject>Waldenstrom Macroglobulinemia - blood</subject><issn>0032-5473</issn><issn>1469-0756</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkcGL1DAUxoO4rGP17EkoCB6EziZNmtdchGVwXdlBV9A9eAlpm85kTJOadGT9783QYXC97CGE5Pvy3vvyQ-gVwUtCKL8YN8NuyfEScLVkTDxBC8K4KDBU_ClaYEzLomJAn6HnMe4wJhQYOUfnnFFChVig21ur4qDyduutjpMO3uatd612U1CT8S5Xrsv1fTrl1oymy5vDhXH54J1vrXfK5hs1DH5U09bo-AKd9cpG_fK4Z-j71Ydvq-ti_eXjp9XlumhYLaaCMSU6gJLXFAQ0tCr7vit7TSsMrIG-T4txQloimKK4bAXGZdezpqkrVaqKZuj9XHfcN4Pu5oGtHIMZVPgjvTLyoeLMVm78b1kyAiKlz9DbY4Hgf-1TdjmY2GprldN-H2VNSM0P1gy9-c-48_uQckdJAHBNakg_nKGL2dUGH2PQ_WkUguUBlTygkhzLhEomVOnF638TnPxHNkkvZt0kLvcnWYWfkgOFSn6-W8n13Y_rK4Cv8ib5383-JvV5rPlfDOitzA</recordid><startdate>19840701</startdate><enddate>19840701</enddate><creator>Levy, Y.</creator><creator>Aviram, M.</creator><creator>Spira, G.</creator><creator>Tatarsky, I.</creator><creator>Brook, G. J.</creator><creator>Carter, A.</creator><general>The Fellowship of Postgraduate Medicine</general><general>Oxford University Press</general><general>BMJ Group</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>19840701</creationdate><title>Plasma cholesterol concentration and extra lipid band in monoclonal gammopathies</title><author>Levy, Y. ; Aviram, M. ; Spira, G. ; Tatarsky, I. ; Brook, G. J. ; Carter, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b489t-44a9d772683797b352ffd2fe35074b7ffb7f4611c194a302c9002df4bb85a2a53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Aged</topic><topic>Apolipoproteins - blood</topic><topic>Apolipoproteins A</topic><topic>Apolipoproteins B</topic><topic>Blood Proteins - analysis</topic><topic>Cholesterol - blood</topic><topic>Cholesterol, HDL</topic><topic>Female</topic><topic>Humans</topic><topic>Hypergammaglobulinemia - blood</topic><topic>Immunoglobulins</topic><topic>Lipids - blood</topic><topic>Lipoproteins, HDL - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multiple Myeloma - blood</topic><topic>Triglycerides - blood</topic><topic>Waldenstrom Macroglobulinemia - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Levy, Y.</creatorcontrib><creatorcontrib>Aviram, M.</creatorcontrib><creatorcontrib>Spira, G.</creatorcontrib><creatorcontrib>Tatarsky, I.</creatorcontrib><creatorcontrib>Brook, G. J.</creatorcontrib><creatorcontrib>Carter, A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Postgraduate medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Levy, Y.</au><au>Aviram, M.</au><au>Spira, G.</au><au>Tatarsky, I.</au><au>Brook, G. J.</au><au>Carter, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Plasma cholesterol concentration and extra lipid band in monoclonal gammopathies</atitle><jtitle>Postgraduate medical journal</jtitle><addtitle>Postgrad Med J</addtitle><date>1984-07-01</date><risdate>1984</risdate><volume>60</volume><issue>705</issue><spage>449</spage><epage>453</epage><pages>449-453</pages><issn>0032-5473</issn><eissn>1469-0756</eissn><abstract>Plasma lipids and lipoproteins were studied in 21 patients with benign monoclonal gammopathy, 21 patients with multiple myeloma and seven patients with Waldenström's macroglobulinaemia. Results were compared with those of a control group, age and sex matched. Low plasma cholesterol levels in all three patient groups were associated with low HDL-cholesterol concentrations. Apo A-I, but not apo B, was significantly reduced. Sixty per cent of the patients exhibited an extra lipid band on plasma lipoprotein electrophoresis, which could be an immunoglobulin-lipid complex. In these patients plasma and LDL-cholesterol levels were significantly lower than in those patients in whom this band was absent. No correlation was found between the severity of the disease and plasma lipid pattern.</abstract><cop>England</cop><pub>The Fellowship of Postgraduate Medicine</pub><pmid>6431399</pmid><doi>10.1136/pgmj.60.705.449</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0032-5473 |
| ispartof | Postgraduate medical journal, 1984-07, Vol.60 (705), p.449-453 |
| issn | 0032-5473 1469-0756 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2417931 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| subjects | Aged Apolipoproteins - blood Apolipoproteins A Apolipoproteins B Blood Proteins - analysis Cholesterol - blood Cholesterol, HDL Female Humans Hypergammaglobulinemia - blood Immunoglobulins Lipids - blood Lipoproteins, HDL - blood Male Middle Aged Multiple Myeloma - blood Triglycerides - blood Waldenstrom Macroglobulinemia - blood |
| title | Plasma cholesterol concentration and extra lipid band in monoclonal gammopathies |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T09%3A15%3A53IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Plasma%20cholesterol%20concentration%20and%20extra%20lipid%20band%20in%20monoclonal%20gammopathies&rft.jtitle=Postgraduate%20medical%20journal&rft.au=Levy,%20Y.&rft.date=1984-07-01&rft.volume=60&rft.issue=705&rft.spage=449&rft.epage=453&rft.pages=449-453&rft.issn=0032-5473&rft.eissn=1469-0756&rft_id=info:doi/10.1136/pgmj.60.705.449&rft_dat=%3Cproquest_pubme%3E81186179%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1770818747&rft_id=info:pmid/6431399&rfr_iscdi=true |