Characterisation of tumour vasculature in mouse brain by USPIO contrast-enhanced MRI

To enhance the success rate of antiangiogenic therapies in the clinic, it is crucial to identify parameters for tumour angiogenesis that can predict response to these therapies. In brain tumours, one such parameter is vascular leakage, which is a response to tumour-derived vascular endothelial growt...

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Veröffentlicht in:	British journal of cancer 2008-06, Vol.98 (11), p.1784-1789
Hauptverfasser:	Gambarota, G, Leenders, W, Maass, C, Wesseling, P, van der Kogel, B, van Tellingen, O, Heerschap, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Animals Biological and medical sciences Biomedical and Life Sciences Biomedicine Blood Blood vessels Blood Volume Blood-brain barrier Brain cancer Brain Neoplasms - blood supply Brain research Cancer Research Capillary Permeability Contrast Media Dextrans Drug Resistance Epidemiology Ferrosoferric Oxide Gadolinium DTPA Glioma - blood supply Humans Image Enhancement Iron Magnetic resonance imaging Magnetic Resonance Imaging - methods Magnetite Nanoparticles Medical research Medical sciences Melanoma Melanoma, Experimental - blood supply Metastasis Mice Molecular Medicine Neoplasm Transplantation Neurology Oncology Oxides Permeability Translational Therapeutics Transplantation, Heterologous Tumors Tumors of the nervous system. Phacomatoses Vascular endothelial growth factor
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