ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma

Gene expression profiling revealed ADAM9 to be distinctly overexpressed in pancreatic ductal adenocarcinoma (PDAC). We examined the relevance of ADAM9 expression in PDAC diagnosis and prognosis. A total of 59 infiltrating PDACs, 32 specimens from patients with chronic pancreatitis, 11 endocrine tumo...

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Veröffentlicht in:	British journal of cancer 2004-03, Vol.90 (5), p.1053-1058
Hauptverfasser:	Grützmann, R, Lüttges, J, Sipos, B, Ammerpohl, O, Dobrowolski, F, Alldinger, I, Kersting, S, Ockert, D, Koch, R, Kalthoff, H, Schackert, H K, Saeger, H D, Klöppel, G, Pilarsky, C
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins Adenocarcinoma - metabolism Adenocarcinoma - pathology Adult Aged Biological and medical sciences Biomarkers, Tumor - metabolism Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma, Acinar Cell - metabolism Carcinoma, Acinar Cell - pathology Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - pathology Cell Differentiation Chronic Disease Cytoplasm Disintegrins - metabolism Drug Resistance Epidemiology Gastroenterology. Liver. Pancreas. Abdomen Humans Immunoenzyme Techniques Islets of Langerhans - metabolism Islets of Langerhans - pathology Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Membrane Proteins - metabolism Metalloendopeptidases - metabolism Middle Aged Molecular and Cellular Pathology Molecular Medicine Oncology Pancreatic cancer Pancreatic Ducts - metabolism Pancreatic Ducts - pathology Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Pancreatitis - metabolism Pancreatitis - pathology Prognosis Survival Rate Tumors
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