TTLL10 is a protein polyglycylase that can modify nucleosome assembly protein 1

Certain proteins can undergo polyglycylation and polyglutamylation. Polyglutamylases (glutamate ligases) have recently been identified in a family of tubulin tyrosine ligase-like (TTLL) proteins. However, no polyglycylase (glycine ligase) has yet been reported. Here we identify a polyglycylase in th...

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Veröffentlicht in:	FEBS letters 2008-04, Vol.582 (7), p.1129-1134
Hauptverfasser:	Ikegami, Koji, Horigome, Daisuke, Mukai, Masahiro, Livnat, Itamar, MacGregor, Grant R., Setou, Mitsutoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals anti-poly-glycine polyclonal antibody Antibodies Carrier Proteins - metabolism cDNA Cell Cycle Proteins - chemistry Cell Cycle Proteins - metabolism complementary DNA Glutamic Acid - analysis Glycylase Glycylation Histone Immunohistochemistry mAb Male Mice Mice, Inbred C57BL Molecular Sequence Data monoclonal antibody NAP Nuclear Proteins - chemistry Nuclear Proteins - metabolism Nucleosome assembly protein Nucleosome Assembly Protein 1 PCR Peptide Synthases - metabolism Polyglutamic Acid - analysis Polyglutamic Acid - immunology Polyglutamic Acid - metabolism polymerase chain reaction post-translational modification Protein Processing, Post-Translational PTM R-polygly Spermatids - chemistry Spermiogenesis TTLL Tubulin tyrosine ligase tubulin tyrosine ligase-like
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