Adverse reactions to rifampicin

This summary of adverse reactions to rifampicin has been prepared with the intention that it will be made available to all those involved in the administration of rifampicin in tuberculosis and leprosy control programmes. The reactions covered comprise those to both daily and intermittent administration, namely cutaneous and gastrointestinal reactions, hepatitis, and thrombocytopenic purpura, and those to intermittent administration only, namely "flu" syndrome, shock, shortness of breath, haemolytic anaemia, and renal failure.