Measurements using the alkaline comet assay predict bladder cancer cell radiosensitivity

In the UK, the two main treatments of invasive bladder cancer are radiotherapy or cystectomy. However, ∼50% of patients undergoing radiotherapy fail to respond. If tumour radiosensitivity could be predicted in advance, it may be possible to improve control rates significantly by selecting for radiot...

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Veröffentlicht in:	British journal of cancer 2003-12, Vol.89 (12), p.2271-2276
Hauptverfasser:	Moneef, M A L, Sherwood, B T, Bowman, K J, Kockelbergh, R C, Symonds, R P, Steward, W P, Mellon, J K, Jones, G D D
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Biomedical and Life Sciences Biomedicine Bladder cancer Cancer Research Carcinoma, Transitional Cell - physiopathology Carcinoma, Transitional Cell - radiotherapy Cell Death Cell Line, Tumor Cell Survival Comet Assay - methods DNA Damage DNA Repair Drug Resistance Epidemiology Humans Medical sciences Molecular and Cellular Pathology Molecular Medicine Nephrology. Urinary tract diseases Oncology Predictive Value of Tests Radiation Tolerance - physiology Tumor Stem Cell Assay - methods Tumors Tumors of the urinary system Urinary Bladder Neoplasms - physiopathology Urinary Bladder Neoplasms - radiotherapy Urinary tract. Prostate gland
Online-Zugang:	Volltext
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