Delivery of Recombinant Adeno-Associated Virus-Mediated Human Tissue Kallikrein for Therapy of Chronic Renal Failure in Rats

The tissue kallikrein-kinin system is important in regulating cardiovascular and renal function, and dysregulation of the system has been implicated in heart and kidney pathologies. These findings suggest that if balance can be restored to the kallikrein-kinin axis, then associated disease progressi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Human gene therapy 2008-04, Vol.19 (4), p.318-330
Hauptverfasser:	LING TU, XIZHEN XU, ZELDIN, Darryl C, DAO WEN WANG, HUAIBING WAN, CHANGQING ZHOU, JUANJUAN DENG, GANG XU, XIAO XIAO, YIPU CHEN, EDIN, Matthew L, VOLTZ, James W
Format:	Artikel
Sprache:	eng
Schlagworte:	Albuminuria Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Applied cell therapy and gene therapy Biological and medical sciences Biotechnology Blood Pressure Bradykinin - pharmacology Chronic kidney failure Creatinine - blood Cyclic GMP - urine Dependovirus - genetics Dosage and administration Drug therapy Fundamental and applied biological sciences. Psychology Gene therapy Genetic Therapy Health aspects Health. Pharmaceutical industry Humans Industrial applications and implications. Economical aspects Kallikrein Kidney - metabolism Kidney - pathology Kidney Failure, Chronic - genetics Kidney Failure, Chronic - therapy Male Medical sciences Models, Animal Nephrectomy Phosphatidylinositol 3-Kinases - metabolism Proto-Oncogene Proteins c-akt - metabolism Rats Rats, Wistar Recombinant Proteins - administration & dosage Recombinant Proteins - genetics Recombinant Proteins - therapeutic use Risk factors Signal Transduction Tissue Kallikreins - administration & dosage Tissue Kallikreins - genetics Tissue Kallikreins - therapeutic use Transforming Growth Factor beta1 - pharmacology Transfusions. Complications. Transfusion reactions. Cell and gene therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!