Increased maternofetal calcium flux in parathyroid hormone-related protein-null mice

The role of parathyroid hormone-related protein (PTHrP) in fetal calcium homeostasis and placental calcium transport was examined in mice homozygous for the deletion of the PTHrP gene ( PTHrP â/â null; NL) compared to PTHrP +/+ (wild-type; WT) and PTHrP +/â (heterozygous; HZ) littermates. Feta...

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Veröffentlicht in:	The Journal of physiology 2008-04, Vol.586 (7), p.2015-2025
Hauptverfasser:	Bond, H., Dilworth, M. R., Baker, B., Cowley, E., Requena Jimenez, A, Boyd, R. D. H., Husain, S. M., Ward, B. S., Sibley, C. P., Glazier, J. D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Transport - physiology Calbindins Calcium - metabolism Female Fetus - metabolism Homeostasis - physiology Integrative Male Maternal-Fetal Exchange - physiology Mice Mice, Knockout Parathyroid Hormone-Related Protein - genetics Parathyroid Hormone-Related Protein - metabolism Placenta - metabolism Placental Circulation - physiology Pregnancy Pregnancy, Animal - metabolism S100 Calcium Binding Protein G - metabolism
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