Laminin-1-induced migration of multiple myeloma cells involves the high-affinity 67 kD laminin receptor

The 67 kD laminin receptor (67LR) binds laminin-1 (LN), major component of the basement membrane, with high affinity. In this study, we demonstrated that human multiple myeloma cell lines (HMCL) and murine 5T2MM cells express 67LR. CD38 bright+ plasma cells in fresh multiple myeloma (MM) bone marrow...

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Veröffentlicht in:	British journal of cancer 2001-11, Vol.85 (9), p.1387-1395
Hauptverfasser:	Vande Broek, I, Vanderkerken, K, De Greef, C, Asosingh, K, Straetmans, N, Van Camp, B, Van Riet, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens Biological and medical sciences Biomedical and Life Sciences Biomedicine Bone marrow Bone Marrow Cells Cancer Research Cell adhesion & migration Cell Movement Chemotactic Factors Cloning Drug Resistance Epidemiology Gene Expression Regulation, Neoplastic Hematologic and hematopoietic diseases Hematology Humans Laminin - pharmacology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Magnetic fields Medical research Medical sciences Metastasis Mice Molecular Medicine Multiple myeloma Multiple Myeloma - pathology Neoplastic Cells, Circulating Oncology Peptides Proteins Receptors, Laminin - physiology Regular regular-article Tumor Cells, Cultured
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