Stimulation of B lymphocytes by cmvIL-10 but not LAcmvIL-10

Abstract Human cytomegalovirus (HCMV) is a widespread pathogen that establishes lifelong latent infection facilitated by numerous mechanisms for modulating the host immune system. The UL111A region of the HCMV genome encodes a homolog of human cellular IL-10 (hIL-10). The viral cytokine, cmvIL-10, e...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 2008-04, Vol.374 (1), p.164-169
Hauptverfasser:	Spencer, Juliet V, Cadaoas, Jaclyn, Castillo, Patricia R, Saini, Vandana, Slobedman, Barry
Format:	Artikel
Sprache:	eng
Schlagworte:	60 APPLIED LIFE SCIENCES B-Lymphocytes - virology Cell Line CELL PROLIFERATION Human cytomegalovirus Humans Immune evasion Infectious Disease Interleukin-10 Interleukin-10 - biosynthesis Lymphocyte Activation LYMPHOCYTES LYMPHOKINES PATHOGENS STAT3 Transcription Factor - metabolism STIMULATION TRANSCRIPTION FACTORS Viral cytokine Viral Proteins - immunology
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