ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo

Oxidative stress is pathogenic in neurological diseases, including stroke. The identity of oxidative stress-inducible transcription factors and their role in propagating the death cascade are not well known. In an in vitro model of oxidative stress, the expression of the bZip transcription factor ac...

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Veröffentlicht in:The Journal of experimental medicine 2008-05, Vol.205 (5), p.1227-1242
Hauptverfasser: Lange, Philipp S, Chavez, Juan C, Pinto, John T, Coppola, Giovanni, Sun, Chiao-Wang, Townes, Tim M, Geschwind, Daniel H, Ratan, Rajiv R
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Sprache:eng
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