'Insulator bodies' are aggregates of proteins but not of insulators

Chromatin insulators are thought to restrict the action of enhancers and silencers. The best‐known insulators in Drosophila require proteins such as Suppressor of Hairy wing (Su(Hw)) and Modifier of mdg4 (Mod(mdg4)) to be functional. The insulator‐related proteins apparently colocalize as nuclear sp...

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Veröffentlicht in:	EMBO reports 2008-05, Vol.9 (5), p.440-445
Hauptverfasser:	Golovnin, Anton, Melnikova, Larisa, Volkov, Ilya, Kostuchenko, Margarita, Galkin, Alexander V, Georgiev, Pavel
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Chromatin Deoxyribonucleic acid DNA DNA-Binding Proteins - metabolism Drosophila Drosophila - cytology Drosophila - embryology Drosophila - genetics Drosophila Proteins - metabolism EMBO09 Embryo, Nonmammalian Genomics Immunohistochemistry Insects Insulator Elements Larva Larvae Male Mod(mdg4) Molecular biology Mutants Mutation Nuclear Proteins - metabolism nuclear speckles Protein Structure, Tertiary Proteins Recombinant Proteins - chemistry Recombinant Proteins - genetics Recombinant Proteins - metabolism Repressor Proteins - metabolism Scientific Report Su(Hw) insulator Transcription Factors - chemistry Transcription Factors - genetics Transcription Factors - metabolism Transgenes Wings, Animal - embryology
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