Antitumor Trans Platinum Adducts of GMP and AMP

Recently it has been shown that several analogues of the clinically ineffective trans-DDP exhibit antitumor activity comparable to that of cis-DDP. The present paper describes the binding of antitumor trans-[PtCl(2)(E-iminoether)(2)] (trans-EE) to guanosinemonophosphate (GMP) and adenosinemonophosph...

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Veröffentlicht in:	Metal-based drugs 2000, Vol.7 (4), p.169-176
Hauptverfasser:	Liu, Y, Sivo, M F, Natile, G, Sletten, E
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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